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A case of gastric leiomyosarcoma in a domestic shorthaircat

机译:短毛猫胃平滑肌肉瘤1例猫

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摘要

Case summaryA 10-year-old male neutered domestic shorthair cat presented with nausea and 1.2 kg weight loss over a 6 month period. Physical examination was unremarkable, and haematological and biochemical results were considered clinically unremarkable. Abdominal ultrasound revealed an 18 mm diameter heterogeneous mass in the stomach at the pyloric sphincter, protruding into the gastric lumen with loss of gastric wall layering. The remainder of the intestinal tract and abdominal viscera were unremarkable and no free fluid was detected. The mass was surgically resected via celiotomy and the adjacent lymph node excised for histopathology. Histopathology of the mass demonstrated neoplastic spindle cell proliferation, which was considered most likely to be of smooth muscle origin, and so a preliminary diagnosis of gastric leiomyosarcoma was given. Complete excision was confirmed. Immunohistochemistry excluded a gastrointestinal stromal cell tumour as a differential and strongly supported the diagnosis of gastric leiomyosarcoma. The cat recovered well postoperatively with supportive treatment. Repeat abdominal ultrasonography 3 and 6 months postoperatively showed no evidence of mass regrowth. Survival time at the time of reporting is 10 months.
机译:病例摘要一只10岁的绝育家猫在短短6个月内出现恶心和体重减轻1.2千克。体格检查无异常,血液学和生化检查结果在临床上无异常。腹部超声检查显示幽门括约肌在胃中直径为18毫米,且异质性肿块伸入胃腔,但胃壁分层消失。其余肠道和腹腔内脏均未见明显变化,也未检测到游离液体。通过切开术手术切除肿块,并切除相邻的淋巴结进行组织病理学检查。肿块的组织病理学表明肿瘤梭形细胞增殖,这被认为最可能是平滑肌起源的,因此对胃平滑肌肉瘤进行了初步诊断。确认完全切除。免疫组织化学排除了胃肠道间质细胞瘤的分化,并强烈支持胃平滑肌肉肉瘤的诊断。这只猫术后接受支持治疗后恢复良好。术后3个月和6个月重复进行腹部超声检查,未发现肿块再生的迹象。报告时的生存时间为10个月。

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