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Jian-Pi-Zhi-Dong-Decoction regulates the expression of glutamate transporters to attenuate glutamate excitotoxicity and exerts anti-tics effects in Tourette syndrome model rats

机译：健脾智通汤调节Tourette综合征模型大鼠谷氨酸转运蛋白的表达减轻谷氨酸兴奋性毒性并具有抗抽动作用

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摘要

PurposeThis study explored whether Jian-Pi-Zhi-Dong-Decoction (JPZDD) could regulate the metabolism of glutamate (GLU) and its transporters in the striatum to exert anti-tics effects in Tourette syndrome (TS) rats.

机译：目的本研究探讨健脾智通汤（JPZDD）是否可以调节纹状体谷氨酸（GLU）的代谢及其在纹状体中的转运，从而对Tourette综合征（TS）大鼠产生抗抽动作用。

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期刊名称 Neuropsychiatric Disease and Treatment
作者
Wenjing Yu; Xiaowei Shi; Xia Cui; Yan Niu; Wen Zhang; Xue Bai; Qian Wang; Lijun Hu; Sumei Wang;
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作者单位

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年(卷),期 2018(14),-1
年度 2018
页码 3381–3392
总页数 12
原文格式 PDF
正文语种
中图分类神经病学;精神病学;
关键词
Jian-Pi-Zhi-Dong-Decoction Tourette syndrome glutamate EAAT1 VGLUT1;

机译：J Ian-pi-Z Hi-dong-decoction tour ET特syndrome glutamate EA at1 V glut1;

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专利

1. Jian-Pi-Zhi-Dong-Decoction regulates the expression of glutamate transporters to attenuate glutamate excitotoxicity and exerts anti-tics effects in Tourette syndrome model rats [J] . Wenjing Yu, Xiaowei Shi, Xia Cui, Neuropsychiatric Disease and Treatment . 2018,第1期

机译：健脾智通汤调节Tourette综合征模型大鼠谷氨酸转运蛋白的表达，减轻谷氨酸兴奋性毒性，并具有抗抽动作用
2. Effects of physical exercise on the developmental expression of hippocampal zinc transporter 1 and glutamate receptor subunit 2, and on cognitive function in a rat model of recurrent neonatal seizure [J] . Hong Ni, Yuwu Jiang, Weiming Jiang, 中国神经再生研究（英文版） . 2009,第001期

机译：体育锻炼对反复发作的新生大鼠癫痫模型海马锌转运蛋白1和谷氨酸受体亚单位2发育表达及认知功能的影响
3. Ulinastatin Exerts the Protective Effects of Lung by Up- Regulating Aquaporins Expression in a Two-Hit Porcine Model of Acute Respiratory Distress Syndrome [J] . HANG Chen Chen, GUO Yu Hong, LI Chun Sheng, 生物医学与环境科学（英文版） . 2021,第012期

机译：Ulinastatin Exerts the Protective Effects of Lung by Up- Regulating Aquaporins Expression in a Two-Hit Porcine Model of Acute Respiratory Distress Syndrome
4. DURATION OF NERVE ROOT COMPRESSIVE TRAUMA MODULATES THE SUBSEQUENT THERMAL HYPERALGESIA SPINAL EXPRESSION OF THE GLUTAMATE TRANSPORTER, GLT1 [C] . Kristen J. Nicholson, Taylor M. Gilliland, Beth A. Winkelstein ASME bioengineering conference . 2014

机译：神经根压迫性创伤的持续时间可调节继发性热痛觉过敏和谷氨酸转运蛋白GLT1的脊髓表达
5. Extracellular glutamate regulates the abundance of glutamate receptors via xCT-like transporters. [D] . Augustin, Hrvoje. 2008

机译：细胞外谷氨酸通过类xCT转运蛋白调节谷氨酸受体的丰度。
6. The chemokine macrophage inflammatory protein-2γ reduces the expression of glutamate transporter-1 on astrocytes and increases neuronal sensitivity to glutamate excitotoxicity [O] . Jie Fang, Deping Han, Jinsheng Hong, 2012

机译：趋化因子巨噬细胞炎性蛋白2γ降低星形胶质细胞上谷氨酸转运蛋白1的表达并增加神经元对谷氨酸兴奋性毒性的敏感性
7. Jian-Pi-Zhi-Dong-Decoction regulates the expression of glutamate transporters to attenuate glutamate excitotoxicity and exerts anti-tics effects in Tourette syndrome model rats [O] . Wenjing Yu, Xiaowei Shi, Xia Cui, 2018

机译：建 - 志东汤调节谷氨酸转运蛋白的表达，抑制谷氨酸兴奋毒性，并在Tourette综合征模型大鼠中发挥抗TICS效应

Jian-Pi-Zhi-Dong-Decoction regulates the expression of glutamate transporters to attenuate glutamate excitotoxicity and exerts anti-tics effects in Tourette syndrome model rats

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