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Mild Cognitive Impairment in Parkinsons Disease: A Review of Current Concepts

机译:帕金森氏病的轻度认知障碍:当前概念的回顾

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摘要

Mild Cognitive Impairment in Parkinson's Disease (PD-MCI) is common and may be associated with accelerated progression to dementia. Considering the importance of this emerging entity, new diagnostic criteria have recently been proposed. Early recognition and accurate classification of PD-MCI could offer opportunities for novel therapeutic interventions. This review discusses current definitions for PD-MCI, the screening tools used, the pattern of cognitive deficits observed, and the predictors of cognitive decline and transition to Parkinson's Disease Dementia. Emerging biomarkers, which may aid diagnosis, are also explored and the role of novel treatment options is considered.
机译:帕金森氏病(PD-MCI)的轻度认知障碍很常见,可能与加速发展为痴呆症有关。考虑到这个新兴实体的重要性,最近提出了新的诊断标准。 PD-MCI的早期识别和准确分类可以为新型治疗干预提供机会。这篇综述讨论了PD-MCI的当前定义,所使用的筛查工具,所观察到的认知缺陷的模式以及认知能力下降和向帕金森氏病痴呆过渡的预测因子。还探讨了可能有助于诊断的新兴生物标志物,并考虑了新型治疗方法的作用。

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