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Single Chain Antibodies Against gp55 of Human Cytomegalovirus (HCMV) for Prophylaxis and Treatment of HCMV Infections

机译：抗人巨细胞病毒（HCMV）gp55的单链抗体用于预防和治疗HCMV感染

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Background:Immunotherapy is a promising prospective new treatment for cytomegalovirus (CMV) infections. Neutralizing effects have been reported using monoclonal antibodies. Recombinant single chain antibodies (scFvs) due to their advantages over monoclonal antibodies are potential alternatives and provide valuable clinical agents.

机译：背景：免疫疗法是针对巨细胞病毒（CMV）感染的有前途的新疗法。已经报道了使用单克隆抗体的中和作用。重组单链抗体（scFvs）由于其优于单克隆抗体的优势而成为潜在的替代方案，并提供了有价值的临床药物。

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期刊名称 Jundishapur Journal of Microbiology
作者
Bahareh Moazen; Elahe Ebrahimi; Foroogh Nejatollahi;
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作者单位

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年(卷),期 2016(9),3
年度 2016
页码 e16241
总页数 5
原文格式 PDF
正文语种
中图分类微生物学 ;
关键词
CMV Gp55 Single-Chain Antibodies Neutralizing Effect;

机译：CMV;Gp55;单链抗体;中和作用;

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专利

1. Single Chain Antibodies Against gp55 of Human Cytomegalovirus (HCMV) for Prophylaxis and Treatment of HCMV Infections [J] . Bahareh Moazen, Elahe Ebrahimi, Foroogh Nejatollahi Jundishapur Journal of Microbiology . 2016 ,第3期

机译：抗人巨细胞病毒（HCMV）gp55的单链抗体，用于预防和治疗HCMV感染
2. Serum antibody response to the gH/gL/pUL128-131 five-protein complex of human cytomegalovirus (HCMV) in primary and reactivated HCMV infections. [J] . Genini E, Percivalle E, Sarasini A, Journal of clinical virology: The official publication of the Pan American Society for Clinical Virology . 2011 ,第2期

机译：在原发性和重新激活的HCMV感染中，血清对人巨细胞病毒（HCMV）的gH / gL / pUL128-131五蛋白复合物的反应。
3. Early neutralizing and glycoprotein B (gB)-specific antibody responses to human cytomegalovirus (HCMV) in immunocompetent individuals with distinct clinical presentations of primary HCMV infection. [J] . Alberola J, Tamarit A, Igual R, Journal of clinical virology: The official publication of the Pan American Society for Clinical Virology . 2000 ,第2期

机译：在具有原发性HCMV感染的不同临床表现的免疫活性个体中，早期中和和糖蛋白B（gB）特异性抗体对人巨细胞病毒（HCMV）的反应。
4. Evaluation of ganciclovir-loaded albumin nanoparticles for the treatment of cytomegalovirus infections [C] . M.Merodio, A.Arnedo, M.Mirshahi, International symposium on controlled release of bioactive materials;Consumer and diversified products conference . 2000

机译：更昔洛韦载白蛋白纳米颗粒治疗巨细胞病毒感染的评估
5. Human cytomegalovirus infection in human umbilical vein endothelial cells; human cytomegalovirus infection in hematopoietic progenitor cells: Model of HCMV latency [D] . Zhuravskya, Tatiana. 1997

机译：人脐静脉内皮细胞中的人巨细胞病毒感染；造血祖细胞中人类巨细胞病毒感染：HCMV潜伏期模型
6. Monoclonal Antibodies to Different Components of the Human Cytomegalovirus (HCMV) Pentamer gH/gL/pUL128L and Trimer gH/gL/gO as well as Antibodies Elicited during Primary HCMV Infection Prevent Epithelial Cell Syncytium Formation [O] . Giuseppe Gerna, Elena Percivalle, Laurent Perez, 2016

机译：针对人类巨细胞病毒（HCMV）五聚体gH / gL / pUL128L和Trimer gH / gL / gO不同成分的单克隆抗体以及原发HCMV感染期间产生的抗体可阻止上皮细胞合胞体形成
7. Association of human cytomegalovirus (HCMV) neutralizing antibodies with antibodies to the HCMV glycoprotein complexes [O] . Miho Shibamura, Tomoki Yoshikawa, Souichi Yamada, 2020

机译：与HCMV糖蛋白复合物的抗体中和抗体的人巨细胞病毒（HCMV）的关联

Single Chain Antibodies Against gp55 of Human Cytomegalovirus (HCMV) for Prophylaxis and Treatment of HCMV Infections

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