P01.104 Evaluation of high signal intensity in globus pallidus and dentate nucleus on unenhanced T1-weighted images after administration of Dotarem vs. Gadavist in brain tumor patients who undergo multiple MRI evaluations

摘要

IntroductionGadolinium-based contrast agents (GBCAs) are routinely used in MRI studies performed for evaluation of brain tumors. Recent studies have demonstrated, progressively increased signal intensity in the globus pallidus (GP) and dentate nucleus (DN) on T1-weighted brain images obtained in patients undergoing repeated MR studies. Linear GBCAs result in more retention and longer time of retention than macrocyclic GBCAs. The aim of this study is to evaluate changes in signal intensity ratios of the GP and the DN on unenhanced T1-weighted images after multiple administrations of macrocyclic GBCAs in brain tumor patients.