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Does Pre-Treatment with High Dose Atorvastatin Prevent Microvascular Dysfunction after Percutaneous Coronary Intervention in Patients with Acute Coronary Syndrome?

机译：大剂量阿托伐他汀治疗前是否可以预防急性冠脉综合征患者经皮冠状动脉介入治疗后微血管功能障碍？

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Background and ObjectivesThere is controversy surrounding whether or not high dose statin administration before percutaneous coronary intervention (PCI) decreases peri-procedural microvascular injury. We performed a prospective randomized study to investigate the mechanisms and effects of pre-treatment high dose atorvastatin on myocardial damage in patients with non-ST-segment elevation acute coronary syndrome (NSTE-ACS) undergoing PCI.

机译：背景与目的围绕经皮冠状动脉介入治疗（PCI）前高剂量他汀类药物的使用是否能减少围手术期微血管损伤尚存争议。我们进行了一项前瞻性随机研究，以研究高剂量阿托伐他汀对接受PCI治疗的非ST段抬高急性冠脉综合征（NSTE-ACS）患者心肌损伤的机制和作用。

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期刊名称 Korean Circulation Journal
作者
Bong-Ki Lee; Bon-Kwon Koo; Chang-Wook Nam; Joon-Hyung Doh; Woo-Young Chung; Byung-Ryul Cho; William F. Fearon;
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作者单位

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年(卷),期 2016(46),4
年度 2016
页码 472–480
总页数 9
原文格式 PDF
正文语种
中图分类
关键词
Acute coronary syndrome Angioplasty Statins IMR Microcirculation;

机译：急性冠状动脉综合征;血管成形术;他汀类药物;IMR;微循环;

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专利

1. Does Pre-Treatment with High Dose Atorvastatin Prevent Microvascular Dysfunction after Percutaneous Coronary Intervention in Patients with Acute Coronary Syndrome? [J] . Lee Bong-Ki, Koo Bon-Kwon, Nam Chang-Wook, Korean Circulation Journal . 2016,第4期

机译：急性冠脉综合征患者经皮冠状动脉介入治疗后，大剂量阿托伐他汀预处理可预防微血管功能障碍吗？
2. Short-term, high-dose Atorvastatin pretreatment to prevent contrast-induced nephropathy in patients with acute coronary syndromes undergoing percutaneous coronary intervention (from the ARMYDA-CIN (atorvastatin for reduction of myocardial damage during angioplasty--contrast-induced nephropathy) trial. [J] . Patti G, Ricottini E, Nusca A, The American Journal of Cardiology . 2011,第1期

机译：短期，大剂量阿托伐他汀预处理可预防接受经皮冠状动脉介入治疗的急性冠状动脉综合征患者的造影剂诱发的肾病（来自ARMYDA-CIN（阿托伐他汀用于减少血管成形术-造影剂诱发的肾病期间的心肌损伤）试验）。
3. Impact of high dose versus low dose atorvastatin on contrast induced nephropathy in diabetic patients with acute coronary syndrome undergoing early percutaneous coronary intervention [J] . Haitham Galal, Wael Nammas, Ayman Samir The Egyptian Heart Journal . 2015,第4期

机译：大剂量阿托伐他汀与小剂量阿托伐他汀对造影剂诱发的急性冠脉综合征的糖尿病肾病的影响
4. Evaluation of Matrix Metalloproteinase-9 (MMP-9) and its tissue inhibitor of metalloproteinase-1 (Timp-1) in patients with coronary syndromes after percutaneous intervention(PCI) [C] . Revnic F., Revnic C.R., Nica A., International Congress on Coronary Artery Disease . 2011

机译：经皮干预后冠状动脉综合征患者中基质金属蛋白酶-9（MMP-9）及其组织抑制剂及其组织抑制剂（PCI）
5. The Association between Unfractionated Heparin and Bivalirudin Used during Percutaneous Coronary Intervention for Stable Angina and Acute Coronary Syndromes and the In-Hospital and Mortality Outcomes Observed across All Body Mass Index Groups [D] . Chen, Christine. 2021

机译：在所有体重指数群体中观察到稳定冠状动脉干预期间使用经皮冠状动脉介入和急性冠状动脉综合征的冠状动脉介入和医院和死亡率结果之间的联合肝素和Bivalirudin之间的关联
6. Effect of loading dose of atorvastatin therapy prior to percutaneous coronary intervention in patients with acute coronary syndrome: a meta-analysis of six randomized controlled trials [O] . Mingfeng Ma, Lixia Bu, Li Shi, 2019

机译：经皮冠状动脉介入治疗前阿托伐他汀治疗负荷剂量对急性冠脉综合征患者的影响：六项随机对照试验的荟萃分析
7. TCT-613 Does High Dose Atorvastatin Pre-treatment Prevent Microvascular Dysfunction After Percutaneous Coronary Intervention in Patients with Acute Coronary Syndrome? : A Randomized Comparison Study Using the Index of Microcirculatory Resistance [O] . Lee Bong-Ki, Choi Wonho, Nam Chang-Wook, 2013

机译：TCT-613大剂量阿托伐他汀预处理可预防急性冠脉综合征患者经皮冠状动脉介入治疗后微血管功能障碍吗？：使用微循环阻力指数的随机比较研究

Does Pre-Treatment with High Dose Atorvastatin Prevent Microvascular Dysfunction after Percutaneous Coronary Intervention in Patients with Acute Coronary Syndrome?

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