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Integrating CRISPR-Cas9 Technology into Undergraduate Courses: Perspectives from a National Science Foundation (NSF) Workshop for Undergraduate Faculty June 2018

机译:将CRISPR-Cas9技术整合到本科课程中:美国国家科学基金会(NSF)本科生研讨会的观点2018年6月

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摘要

As CRISPR (clustered regularly interspaced short palindromic repeats)-Cas9 technology becomes more mainstream in life science research, it becomes critical for undergraduate instructors to devise engaging ways to bring the technology into their classrooms. To help meet this challenge, the National Science Foundation sponsored a workshop for undergraduate instructors in June 2018 at The Ohio State University in conjunction with the annual Association of Biology Laboratory Educators meeting based on a workflow developed by the workshop’s facilitators. Over the course of two and a half days, participants worked through a modular workflow for the use of CRISPR-Cas9 in a course-based (undergraduate) research experience (CURE) setting while discussing the barriers each of their institutions had to implementing such work, and how such barriers could be overcome. The result of the workshop was a team with newfound energy and confidence to implement CRISPR-Cas9 technology in their courses and the development of a community of undergraduate educators dedicated to supporting each other in the implementation of the workflow either in a CURE or modular format. In this article, we review the activities and discussions from the workshop that helped each participant devise their own tailored approaches of how best to bring this exciting new technology into their classes.
机译:随着CRISPR(聚簇的规则间隔的短回文重复序列)-Cas9技术在生命科学研究中变得更加主流,对于大学生讲师而言,设计出引人入胜的方法以将该技术带入课堂变得至关重要。为了帮助应对这一挑战,美国国家科学基金会(National Science Foundation)于2018年6月在俄亥俄州立大学举办了一次针对本科讲师的讲习班,并根据该讲习班的主持人开发的工作流程,与年度生物学实验室教育家协会的年度会议相结合。在为期两天半的过程中,参与者在基于课程的(本科)研究经验(CURE)设置中,通过模块化工作流程使用CRISPR-Cas9,同时讨论了每个机构实施此类工作的障碍,以及如何克服这些障碍。研讨会的结果是一个充满新活力和信心的团队,在他们的课程中实施CRISPR-Cas9技术,并发展了一个致力于相互支持的以CURE或模块化格式实施工作流程的大学教育者社区。在本文中,我们回顾了研讨会上的活动和讨论,这些活动和讨论帮助每个参与者设计了自己的量身定制的方法,以最佳方式将这一激动人心的新技术引入他们的课堂。

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