Production of Composite Scaffold Containing Silk Fibroin Chitosan and Gelatin for 3D Cell Culture and Bone Tissue Regeneration

摘要

BackgroundBone tissue engineering, a powerful tool to treat bone defects, is highly dependent on use of scaffolds. Both silk fibroin (SF) and chitosan (Cs) are biocompatible and actively studied for reconstruction of tissue engineering. Gelatin (Gel) is also widely applied in the biomedical field due to its low antigenicity and physicochemical stability.