Osmotic and diffusive flows in single-file pores: new approach to modeling pore occupancy states

摘要

BackgroundThe relation between osmotic permeability, Pf, diffusion permeability, Pd, and the number of water molecules, Np, in the single-file membrane pore remains an open question. Theoretical analyses, empirical studies on aquaporins and nanotubes, and molecular dynamics simulations have yet to provide a consensus view.