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Trends In Acoustic Neuroma Management: A 20-Year Review of the Oxford Skull Base Clinic

机译:声学神经瘤管理的趋势:牛津头骨基础诊所的20年回顾。

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摘要

>Objective To describe the change in the management of acoustic neuromas at one United Kingdom center over a 20-year period and to compare this with what is known regarding trends in practice on a national and international scale.>Design, Setting, and Participants Data was collected prospectively on all patients attending the Oxford Skull Base Clinic between 1990 and 2009.>Main Outcome Measures The proportion of patients managed initially by observation versus radiotherapy versus surgery was recorded for each year.>Results Significantly more patients received radiation treatment (instead of surgery) between 2000 and 2009 when compared with 1990 to 1999. Compared with national audit data, the Oxford Skull Base Clinic treats a higher proportion of patients with radiotherapy and significantly lower proportion with surgery, though the trend nationally is toward more observation and radiotherapy and less surgery.>Conclusion Surgery will remain crucial in the management of some patients with acoustic neuromas (usually those with the larger tumors where radiosurgery is recognized to be less appropriate), but using current trends to predict future practice would suggest that alternative nonmicrosurgical treatment may play an increasingly important role in the future.
机译:>目的描述一个英国中心20年来声学神经瘤的管理变化,并将其与国家和国际范围内实践趋势的已知变化进行比较。 >设计,设置和参与者前瞻性地收集了1990年至2009年间所有在牛津头骨基础诊所就诊的患者的数据。>主要结果指标 >结果与2000年至1990年至1999年相比,在2000年至2009年之间,接受放射治疗(而非手术)的患者显着增加。与国家审核数据相比,牛津颅骨基础诊所治疗尽管全国的趋势是更多地进行观察和放射治疗,但手术较少。>结论手术对于某些听神经瘤患者(通常是那些肿瘤较大的患者,通常认为放射外科治疗不太合适)的治疗仍将是至关重要的,但是利用当前趋势来预测未来的实践将提示替代性非显微外科治疗可能在未来起着越来越重要的作用。

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