18F-Fluoromethylcholine-positron emission tomography/computed tomography for diagnosing bone and lymph node metastases in patients with intermediate- or high-risk prostate cancer

摘要

BackgroundThe use of molecular imaging in staging of prostate cancer (PC) is debated. In patients with newly diagnosed PC we investigated the diagnostic value of ¹⁸F-flouromethylcholine positron emission tomography/computed tomography (¹⁸F-FCH-PET/CT) for the detection of bone and lymph node metastases compared to whole-body bone scintigraphy (WBS) with technetium-99-methylene diphosphonate (^99mTc-MDP) and results of extended pelvic lymph node dissection, respectively.