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A Novel Automatic Rapid Diagnostic Test Reader Platform

机译:新型自动快速诊断测试阅读器平台

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摘要

A novel automatic Rapid Diagnostic Test (RDT) reader platform is designed to analyze and diagnose target disease by using existing consumer cameras of a laptop-computer or a tablet. The RDT reader is useable with numerous lateral immunochromatographic assays and similar biomedical tests. The system has two different components, which are 3D-printed, low-cost, tiny, and compact stand and a decision program named RDT-AutoReader 2.0. The program takes the image of RDT, crops the region of interest (ROI), and extracts the features from the control end test lines to classify the results as invalid, positive, or negative. All related patient's personal information, image of ROI, and the e-report are digitally saved and transferred to the related clinician. Condition of the patient and the progress of the disease can be monitored by using the saved data. The reader platform has been tested by taking image from used cassette RDTs of rotavirus (RtV)/adenovirus (AdV) and lateral flow strip RDTs of Helicobacter pylori (H. pylori) before discarding them. The created RDT reader can also supply real-time statistics of various illnesses by using databases and Internet. This can help to inhibit propagation of contagious diseases and to increase readiness against epidemic diseases worldwide.
机译:一种新颖的自动快速诊断测试(RDT)读取器平台旨在使用笔记本电脑或平板电脑的现有消费类相机来分析和诊断目标疾病。 RDT读取器可用于多种横向免疫色谱分析和类似的生物医学测试。该系统具有两个不同的组件,分别是3D打印,低成本,小巧而紧凑的支架,以及一个名为RDT-AutoReader 2.0的决策程序。该程序获取RDT的图像,裁剪感兴趣的区域(ROI),并从控制端测试线中提取特征,以将结果分类为无效,阳性或阴性。所有相关患者的个人信息,ROI图像和电子报告均以数字方式保存,并传输给相关临床医生。通过使用保存的数据可以监视患者的状况和疾病的进展。该读取器平台已经过测试,可以在丢弃轮状病毒(RtV)/腺病毒(AdV)的二手盒式RDT和幽门螺杆菌(H. pylori)的侧向流动条RDT之前拍摄图像。创建的RDT阅读器还可以通过使用数据库和Internet提供各种疾病的实时统计信息。这可以帮助抑制传染性疾病的传播,并增强全球抗击流行病的能力。

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