Full-thickness burn and other types of deep skin loss will result in scar formation. For at least partial replacement of the lost dermal layer, there are several options to use biotechnologically derived extracellular matrix components or tissue scaffolds of cadaver skin origin. In a survey, we have collected data on 18 pts who have previously received acellular dermal implant Alloderm. The age of these patients at the injury varied between 16 months and 84 years. The average area of the implants was 185 cm2. Among those, 15 implant sites of 14 patients were assessed at an average of 50 months after surgery. The scar function was assessed by using the modified Vancouver Scar Scale. We have found that the overall scar quality and function was significantly better over the implanted areas than over the surrounding skin. Also these areas received a better score for scar height and pliability. Our findings suggest that acellular dermal implants are especially useful tools in the treatment of full-thickness burns as well as postburn scar contractures.
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机译：全层烧伤和其他类型的深层皮肤损失会导致疤痕形成。为了至少部分置换丢失的真皮层，有几种选择可以使用生物技术衍生的尸体皮肤来源的细胞外基质成分或组织支架。在一项调查中，我们收集了先前接受脱细胞真皮植入物Alloderm的18位患者的数据。这些患者受伤时的年龄在16个月至84岁之间。植入物的平均面积为185 cm 2 。在这些患者中，平均术后50个月评估了14例患者的15个植入部位。通过使用改良的温哥华疤痕量表评估疤痕功能。我们发现，在植入区域的整体疤痕质量和功能明显好于周围皮肤。同样，这些区域在疤痕高度和柔韧性方面得分更高。我们的发现表明，脱细胞真皮植入物在治疗全层烧伤和烧伤后瘢痕挛缩方面特别有用。
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