The regenerative capacity of most tissues declines dramatically after embryonic development and during post-natal life. The underlying mechanisms of this phenomenon are incompletely understood. In a recent issue of Cell, Shyh-Chang and colleagues provide experimental evidence that Lin28 prolongs youthful regenerative capacity by increasing oxidative glucose metabolism (Shyh-Chang et al, ).
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机译:大多数组织的再生能力在胚胎发育后和出生后生命中急剧下降。这种现象的潜在机制尚不完全清楚。在最近一期的Cell中,Shyh-Chang及其同事提供了实验证据,证明Lin28通过增加氧化葡萄糖代谢来延长年轻的再生能力(Shyh-Chang et al。)
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