Medicinal plants are traditionally used for the treatment of human infections. The present study was undertaken to investigate Bergenia ciliata, Jasminum officinale, and Santalum album for their potential activity against human bacterial pathogens.B. ciliata, J. officinale, and S. album extracts were prepared in cold and hot water. The activity of plant extracts and selected antibiotics was evaluated against five bacterial pathogens including Staphylococcus aureus, Bacillus subtilis, Proteus vulgaris, Pseudomonas aeruginosa, and Escherichia coli using agar well diffusion method.Among the three medicinal plants, B. ciliata extracts displayed potential activity against bacterial pathogens. Cold water extract of Bergenia ciliate showed the highest activity against B. subtilis, which is comparable with a zone of inhibition exhibited by ceftriaxone and erythromycin. J. officinale and S. album extracts demonstrated variable antibacterial activity. Further studies are needed to explore the novel antibacterialbioactive molecules.
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机译：传统上，药用植物用于治疗人类感染。进行本研究是为了研究卑尔根（Bergenia ciliata），茉莉（Jasminum officinale）和桑塔姆（Santalum）相册对人类细菌病原体的潜在活性。在冷热水中制备纤毛，J。officinale和S. album提取物。通过琼脂井扩散法评估了植物提取物和所选抗生素对五种细菌病原体的活性，包括金黄色葡萄球菌，枯草芽孢杆菌，寻常变形杆菌，铜绿假单胞菌和大肠杆菌，在这三种药用植物中，纤毛芽孢杆菌提取物均显示出潜在的活性细菌病原体。卑尔根虫纤毛虫的冷水提取物显示出最高的抗枯草芽孢杆菌活性，这与头孢曲松和红霉素所表现出的抑制作用区相当。 J. officinale和S. album提取物表现出不同的抗菌活性。需要进一步研究以探索新型抗菌剂生物活性分子。
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