An investigation of effectiveness of topical treatment of nonhealing chronic venous leg ulcers with propolis ointment was conducted. 56 patients were included in the study and randomized into two groups. In group 1, there were 28 patients (ulceration area: 6.9–9.78 cm2) treated by means of topical propolis ointment application and short stretch bandage compression. In group 2, there were 29 patients (ulceration area: 7.2–9.4 cm2) treated by means of Unna boot leg compression without topical propolis treatment. In the study, the efficacy of both treatment methods in patients with resistive venous leg ulcers was compared. The ulceration of patients from group 1 healed completely after 6 weeks of therapy in all cases. In all patients from group 2, the process of healing was longer but successfully completed after 16 weeks of the therapy. We found that an adjunctive propolis ointment treatment increases the efficacy of the short stretch bandage compression stocking, and this combined treatment is more effective than Unna's boot compression alone.
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机译：进行了局部治疗蜂胶软膏治疗无法治愈的慢性静脉曲张溃疡的效果的调查。本研究包括56例患者，随机分为两组。在第1组中，有28例患者（溃疡面积：6.9–9.78 cm 2 ）采用局部蜂胶软膏加短绷带绷带加压治疗。在第2组中，有29例患者（溃疡面积：7.2–9.4 cm 2 ）通过Unna引导腿加压治疗而未进行局部蜂胶治疗。在这项研究中，比较了两种治疗方法在抵抗性小腿静脉溃疡患者中的疗效。在所有情况下，治疗6周后，第1组患者的溃疡完全愈合。在第2组的所有患者中，愈合过程更长，但在治疗16周后成功完成。我们发现蜂胶辅助软膏治疗可提高短弹力绷带加压袜的功效，这种联合治疗比单独的Unna靴套加压更有效。
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