Recommendations from the ESO-Karolinska Stroke Update ConferenceStockholm 13–15 November 2016

摘要

>About the meeting: The purpose of the European Stroke Organisation (ESO)-Karolinska Stroke Update Conference is to provide updates on recent stroke therapy research and to give an opportunity for the participants to discuss how these results may be implemented into clinical routine. Several scientific sessions discussed in the meeting and each session produced consensus statements. The meeting started 20 years ago as Karolinska Stroke Update, but since 2014, it is a joint conference with ESO. Importantly, it provides a platform for discussion on the ESO guidelines process and on recommendations to the ESO guidelines committee on specific topics. By this, it adds a direct influence from stroke professionals otherwise not involved in committees and work groups on the guidelines procedure. The discussions at the conference may also inspire new guidelines when motivated. The topics raised at the meeting are selected by the scientific programme committee mainly based on recent important scientific publications. The ESO-Karolinska Stroke Update consensus statement and recommendations will be published every 2 years and it will work as implementation of ESO-guidelinesBackgroundThis year’s ESO-Karolinska Stroke Update Meeting was held in Stockholm on 13–15 November 2016. There were 10 scientific sessions discussed in themeeting and each session produced a consensus statement (Fullversion with background, issues, conclusions and references arepublished as web-material and at and ) and recommendationswhich were prepared by a writing committee consisting of session chair(s),secretary and speakers and presented to the 312 participants of the meeting.In the open meeting, general participants commented on the consensusstatement and recommendations and the final document were adjusted based onthe discussion from the general participants.>Recommendations (grade of evidence) were graded according to the1998 Karolinska Stroke Update meeting with regard to the strength ofevidence. >Grade A Evidence: Strong support from randomisedcontrolled trials and statistical reviews (at least one randomisedcontrolled trial plus one statistical review). >Grade BEvidence: Support from randomised controlled trials andstatistical reviews (one randomised controlled trial or one statisticalreview). >Grade C Evidence: No reasonable support fromrandomised controlled trials, recommendations based on small randomisedand/or non-randomised controlled trials evidence.