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How Many People have Alcohol Use Disorders? Using the Harmful Dysfunction Analysis to Reconcile Prevalence Estimates in Two Community Surveys

机译:有多少人有饮酒障碍?使用有害功能障碍分析调和两次社区调查中的患病率估计

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摘要

Community prevalence rates of alcohol use disorders (AUDs) provided by epidemiological studies using DSM-based diagnostic criteria pose several challenges: the rates appear implausibly high to many epidemiologists; they do not converge across similar studies; and, due to low service utilization by those diagnosed as disordered, they yield estimates of unmet need for services so high that credibility for planning purposes is jeopardized. For example, two early community studies using DSM diagnostic criteria, the Epidemiologic Catchment Area Study (ECA) and the National Comorbidity Survey (NCS), yielded lifetime AUD prevalence rates of 14 and 24%, respectively, with NCS unmet need for services 19% of the entire population. Attempts to address these challenges by adding clinical significance requirements to diagnostic criteria have proven unsuccessful. Hypothesizing that these challenges are due to high rates of false-positive diagnoses of problem drinking as AUDs, we test an alternative approach. We use the harmful dysfunction (HD) analysis of the concept of mental disorder as a guide to construct more valid criteria within the framework of the standard out-of-control model of AUD. The proposed HD criteria require harm and dysfunction, where harm can be any negative social, personal, or physical outcome, and dysfunction requires either withdrawal symptoms or inability to stop drinking. Using HD criteria, ECA and NCS lifetime prevalences converge to much-reduced rates of 6 and 6.8%, respectively. Due to higher service utilization rates, NCS lifetime unmet need is reduced to 3.4%. Service use and duration comparisons suggest that HD criteria possess increased diagnostic validity. Moreover, HD criteria eliminate 90% of transient teenage drinking from disorder status. The HD version of the out-of-control model thus potentially resolves the three classic prevalence challenges while offering a more rigorous approach to distinguishing AUDs from problematic drinking.
机译:流行病学研究使用基于DSM的诊断标准提供的酒精使用障碍(AUDs)社区患病率带来了一些挑战:对于许多流行病学家来说,这一比率似乎高得令人难以置信;他们没有在相似的研究中融合;并且,由于被诊断为无序的人们的服务使用率低,他们得出的对服务的未满足需求的估计值如此之高,以至于计划目的的信誉受到损害。例如,两项使用DSM诊断标准的早期社区研究(流行病学集水区研究(ECA)和国家合并症调查(NCS))分别使终身AUD患病率分别为14%和24%,而NCS未满足服务需求的比例为19%整个人口中通过在诊断标准中增加临床意义的要求来解决这些挑战的尝试已证明是不成功的。假设这些挑战是由于误饮酒对澳元的误诊率较高,我们测试了另一种方法。我们使用对精神障碍概念的有害功能障碍(HD)分析作为指导,以在AUD标准失控模型的框架内构建更有效的标准。拟议的HD标准要求伤害和功能障碍,其中伤害可能是任何负面的社会,个人或身体后果,而功能障碍则需要戒断症状或无法戒酒。使用高清标准,ECA和NCS的一生患病率分别降低了6%和6.8%。由于更高的服务利用率,NCS生命周期未满足的需求减少到3.4%。服务使用和持续时间的比较表明,HD标准具有更高的诊断有效性。此外,高清标准可消除90%的青少年暂时性饮酒异常状态。因此,高清版失控模型有可能解决三个经典的流行性挑战,同时提供更严格的方法来区分澳元和有问题的饮酒。

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