The 3D Genome Browser: a web-based browser for visualizing 3D genome organization and long-range chromatin interactions

摘要

Here, we introduce the 3D Genome Browser, , which allows users to conveniently explore both their own and over 300 publicly available chromatin interaction data of different types. We design a new binary data format for Hi-C data that reduces the file size by at least a magnitude and allows users to visualize chromatin interactions over millions of base pairs within seconds. Our browser provides multiple methods linking distal cis-regulatory elements with their potential target genes. Users can seamlessly integrate thousands of other omics data to gain a comprehensive view of both regulatory landscape and 3D genome structure.Electronic supplementary materialThe online version of this article (10.1186/s13059-018-1519-9) contains supplementary material, which is available to authorized users.