BackgroundCondensins are multi-subunit protein complexes that are essential for chromosome condensation during mitosis and meiosis, and play key roles in transcription regulation during interphase. Metazoans contain two condensins, I and II, which perform different functions and localize to different chromosomal regions. Caenorhabditis elegans contains a third condensin, IDC, that is targeted to and represses transcription of the X chromosome for dosage compensation.
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机译：背景浓缩素是多亚基蛋白复合物，对于有丝分裂和减数分裂过程中的染色体浓缩至关重要，并且在间期转录调控中起关键作用。后生动物包含两个凝缩蛋白I和II，它们执行不同的功能并位于不同的染色体区域。秀丽隐杆线虫包含第三种凝缩素，I DC ，其针对并抑制X染色体的转录以进行剂量补偿。
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