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Endoluminal occlusion devices: technology update

机译:腔内阻塞装置:技术更新

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摘要

Endoluminal occlusion has been performed since the early beginning of interventional radiology. Over recent decades, major technological advances have improved the techniques used and different devices have been developed for changing conditions. Most of these occlusion devices have been implemented in the vascular territory. Early embolization materials included glass particles, hot contrast, paraffin, fibrin, and tissue fragments such as muscle fibers and blood clots; today, occlusion materials include metallic devices, particles, and liquid materials, which can be indicated for proximal or distal occlusion, high-flow and low-flow situations, and in large-caliber and small-caliber vessels, based on need. Technological progress has led to a decreased size of delivery catheters, and an increase in safety due to release systems that permit the withdrawing and replacement of embolization material. Furthermore, bioactive embolization materials have been developed to increase the efficacy of embolization or the biological effect of medication. Finally, materials have been modified for changing indications. Intravascular stents were initially developed to keep an artery open; however, by adding a covering membrane, these stents can be used to occlude the wall of a vessel or other endoluminal structures. This article gives an overview of the devices most utilized for occlusion of endoluminal structures, as well as their major purpose in the endovascular territory.
机译:自介入放射学的早期开始就进行了腔内阻塞。在最近的几十年中,重大的技术进步已经改善了所使用的技术,并且已经开发出用于改变条件的不同设备。这些阻塞装置大多数已在血管区域实施。早期的栓塞材料包括玻璃颗粒,热对比剂,石蜡,纤维蛋白和组织碎片,例如肌肉纤维和血凝块。如今,阻塞材料包括金属装置,颗粒和液体材料,可根据需要用于近端或远端阻塞,高流量和低流量情况,以及大口径和小口径容器。技术进步已导致输送导管的尺寸减小,并且由于允许抽出和更换栓塞材料的释放系统而增加了安全性。此外,已经开发了生物活性栓塞材料以增加栓塞功效或药物的生物学作用。最后,已对材料进行了修改以更改指示。最初开发血管内支架以保持动脉畅通。然而,通过添加覆盖膜,这些支架可用于阻塞血管壁或其他腔内结构。本文概述了最常用于阻塞腔内结构的装置及其在血管内区域的主要用途。

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