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Spindle Cell Epulis in an 8-Month-Old Child: A Histologic Variant of Congenital Granular Cell Epulis?

机译:8个月大儿童的纺锤体细胞脓肿:先天性颗粒细胞脓肿的组织学变异?

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摘要

A case of an epulis in an 8-month-old boy is reported. The tumor was localized on the mandibular alveolar ridge and, according to the parents, was a recurrence of a congenital tumor excised when the boy was 2 months old. Microscopically, it was composed of many spindled or ovoid cells with vesicular nuclei and non-granular eosinophilic cytoplasm, and covered by acanthotic parakeratinized squamous epithelium with broad rete pegs. Immunohistochemically, the spindled and ovoid cells were intensely positive for vimentin and neuron-specific enolase, and negative for S-100 protein. The final diagnosis was spindle cell epulis. The possible correlation of this lesion with congenital granular cell epulis is discussed.
机译:据报道,在一个8个月大的男孩中有一口脓疱病。父母认为,该肿瘤位于下颌牙槽上,是男孩2个月大时切除的先天性肿瘤的复发。在显微镜下,它由许多纺锤形或卵形细胞组成,具有泡状细胞核和非颗粒性嗜酸性细胞质,并被棘皮化角化角化鳞状上皮覆盖着宽的网状钉。免疫组织化学观察,纺锤形和卵形细胞对波形蛋白和神经元特异性烯醇化酶呈强阳性,而对S-100蛋白呈阴性。最终的诊断是纺锤状细胞疱疹。讨论了该病变与先天性颗粒细胞脓肿的可能相关性。

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