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Periodontitis in rheumatoid arthritis patients abundance and association with disease activity

机译:类风湿关节炎患者的牙周炎丰富度及其与疾病活动的关系

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摘要

>Background: There are some discrepancy in association between activity of rheumatoid arthritis (RA) and periodontitis. The aim of this study was to evaluate the periodontal status of outpatients with RA. >Methods: The study was conducted in 2013-14 in a rheumatology clinic in Sari, north of Iran on 74 patients with RA. Evaluation of RA disease activity was according to disease activity score 28 (DAS28). Periodontitis was evaluated by probing depth (PD), gingival index (GI), clinical attachment level (CAL index), plaque index (PI), and panoramic X-ray. Statistical analysis included independent ttest and Mann-Whitney U test for quantitative, and chi square and OR for qualitative variables and evaluation of RA activity and periodontitis severity. >Results: The mean±SD of age and disease duration were 47.01±8.1 and 8.93±8.6 years, respectively and the mean±SD number of teeth was 20.70±6.8. Twenty-seven (36.5%) patients had moderate to severe disease. Forty-seven cases (63.5%) were found with periodontitis and 14 (12.2%) were identified to have moderate to severe periodontitis, unrelated to disease activity (p=0.22). For active/inactive periodontitis OR =1.33 (95% CI: 0.46 - 3.87) was computed. There was no association between RA disease activity and number of teeth, CAL, PI, PD, and GI, (p>0.05). >Conclusion: About 60% of RA patients suffered from periodontitis, but there was not any significant relation between RA diseaseactivity and severity of periodontitis. Periodontitis may interfere with management and follow up of RA, so periodic periodontal examinationis suggested in these patients.
机译:>背景:类风湿关节炎(RA)与牙周炎之间存在一定的差异。这项研究的目的是评估门诊RA患者的牙周状况。 >方法:该研究于2013-14年度在伊朗北部萨里的风湿病诊所对74例RA患者进行。根据疾病活动评分28(DAS28)评估RA疾病活动。通过探测深度(PD),牙龈指数(GI),临床依从水平(CAL指数),牙菌斑指数(PI)和全景X线评估牙周炎。统计分析包括定量的独立t检验和Mann-Whitney U检验,定性变量的卡方检验或OR检验以及RA活动和牙周炎严重程度的评估。 >结果:年龄和疾病持续时间的平均±SD分别为47.01±8.1和8.93±8.6岁,牙齿的平均±SD数为20.70±6.8。二十七(36.5%)名患者患有中度至重度疾病。发现47例(63.5%)患有牙周炎,其中14例(12.2%)被确定为中度至重度牙周炎,与疾病活动无关(p = 0.22)。对于活动性/非活动性牙周炎,OR = 1.33(95%CI:0.46-3.87)。 RA疾病活动性与牙齿数量,CAL,PI,PD和GI之间没有关联(p> 0.05)。 >结论:大约60%的RA患者患有牙周炎,但与RA疾病之间没有任何显着关系牙周炎的活动和严重程度。牙周炎可能会干扰RA的治​​疗和随访,因此应定期进行牙周检查建议在这些患者中使用。

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