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Novel Approach in the Use of Plasma Spray: Preparation of Bulk Titanium for Bone Augmentations

机译:使用等离子喷涂的新方法:制备用于骨增强的块状钛

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摘要

Thermal plasma spray is a common, well-established technology used in various application fields. Nevertheless, in our work, this technology was employed in a completely new way; for the preparation of bulk titanium. The aim was to produce titanium with properties similar to human bone to be used for bone augmentations. Titanium rods sprayed on a thin substrate wire exerted a porosity of about 15%, which yielded a significant decrease of Young′s modulus to the bone range and provided rugged topography for enhanced biological fixation. For the first verification of the suitability of the selected approach, tests of the mechanical properties in terms of compression, bending, and impact were carried out, the surface was characterized, and its compatibility with bone cells was studied. While preserving a high enough compressive strength of 628 MPa, the elastic modulus reached 11.6 GPa, thus preventing a stress-shielding effect, a generally known problem of implantable metals. U-2 OS and Saos-2 cells derived from bone osteosarcoma grown on the plasma-sprayed surface showed good viability.
机译:等离子热喷涂是在各种应用领域中广泛使用的通用技术。然而,在我们的工作中,这项技术以全新的方式被采用。用于制备散装钛。目的是生产具有与人骨相似的特性的钛,以用于骨骼增强。喷涂在细金属丝上的钛棒的孔隙率约为15%,这导致杨氏模量显着降低至骨骼范围,并提供了坚固的外形以增强生物固定性。为了首次验证所选方法的适用性,进行了压缩,弯曲和冲击方面的机械性能测试,对表面进行了表征,并研究了其与骨细胞的相容性。在保持628 MPa的足够高的抗压强度的同时,弹性模量达到了11.6 GPa,从而防止了应力屏蔽效应,这是可植入金属的普遍已知问题。血浆喷雾表面生长的骨骨肉瘤来源的U-2 OS和Saos-2细胞显示出良好的生存能力。

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