首页> 美国卫生研究院文献>Current Controlled Trials in Cardiovascular Medicine >Protocol for TRAUMADORNASE: a prospective randomized multicentre double-blinded placebo-controlled clinical trial of aerosolized dornase alfa to reduce the incidence of moderate-to-severe hypoxaemia in ventilated trauma patients

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Protocol for TRAUMADORNASE: a prospective randomized multicentre double-blinded placebo-controlled clinical trial of aerosolized dornase alfa to reduce the incidence of moderate-to-severe hypoxaemia in ventilated trauma patients

机译：TRAUMADORNASE方案：前瞻性随机多中心双盲安慰剂对照的雾化阿糖化酶阿尔法降低通气性创伤患者中低度至重度低氧血症发生率的临床试验

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Aerogen (Ireland) will provide nebulizers to study centres at an estimated value of 28k€.

机译：Aerogen（爱尔兰）将向研究中心提供雾化器，估计价值为28,000欧元。

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期刊名称 Current Controlled Trials in Cardiovascular Medicine
作者
Julien Pottecher; Eric Noll; Marie Borel; Gérard Audibert; Sébastien Gette; Christian Meyer; Elisabeth Gaertner; Vincent Legros; Raphaël Carapito; Béatrice Uring-Lambert; Erik Sauleau; Walter G. Land; Seiamak Bahram; Alain Meyer; Bernard Geny; Pierre Diemunsch;
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年(卷),期 2020(21),-1
年度 2020
页码 -1
总页数 13
原文格式 PDF
正文语种
中图分类心血管疾病;
关键词
Acute respiratory distress syndrome; Adult; Hypoxaemia; Multiple trauma; Deoxyribonuclease I; Neutrophil extracellular traps; Randomized controlled trial;

机译：急性呼吸窘迫综合征;成人;低氧血症;多发性创伤;脱氧核糖核酸酶I;中性粒细胞胞外诱集;随机对照试验;

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1. Protocol for TRAUMADORNASE: a prospective, randomized, multicentre, double-blinded, placebo-controlled clinical trial of aerosolized dornase alfa to reduce the incidence of moderate-to-severe hypoxaemia in ventilated trauma patients [J] . Julien Pottecher, Eric Noll, Marie Borel, Trials . 2020,第1期

机译：创伤酶协议：雾化DORNASE ALFA的前瞻性，随机，多环境，双盲，安慰剂对照临床试验，降低通风创伤患者中度至严重的低氧血症的发病率
2. Efficacy and safety of aerosolized intra-tracheal dornase alfa administration in patients with SARS-CoV-2-induced acute respiratory distress syndrome (ARDS): a structured summary of a study protocol for a randomised controlled trial [J] . J. P. Desilles, C. Gregoire, C. Le Cossec, Trials . 2020,第1期

机译：SARS-COV-2诱导的急性呼吸窘迫综合征（ARDS）患者雾化气膜内疣蛋白酶ALFA管理的疗效和安全性：随机对照试验的研究方案的结构化概述
3. Multicentre randomised controlled trial to investigate the usefulness of continuous pneumatic regulation of tracheal cuff pressure for reducing ventilator-associated pneumonia in mechanically ventilated severe trauma patients: the AGATE study protocol [J] . Jérémy Guénézan, Jean-Michel Constantin, Karim Asehnoune, BMJ Open . 2017,第8期

机译：多中心随机对照试验研究连续气道调节气管袖带压在减轻机械通气严重创伤患者中呼吸机相关性肺炎中的作用：AGATE研究方案
4. Effects of 650 nm-10.6 μm Combined Laser Acupuncture-Moxibustion on Knee Osteoarthritis:A Randomized,Double-blinded and Placebo-controlled Clinical Trial [C] . SHEN Xue-yong, DING Guang-hong, WU Fan, The 3rd Workshop on Scientific Approaches to Chinese Medicine(第三届中医科学研究方法研讨会)论文集 . 2008

机译：650 nm-10.6μm联合激光针灸对膝骨关节炎的影响：一项随机，双盲和安慰剂对照的临床试验
5. Efficacy of the Chinese herbal formula CUF2 in the treatment of childhood asthma: Animal experiment, in vitro study and randomized, double-blinded, placebo-controlled clinical trial. [D] . Wong, Yeuk Oi. 2006

机译：中药配方CUF2在治疗儿童哮喘中的功效：动物实验，体外研究以及随机，双盲，安慰剂对照的临床试验。
6. Efficacy and safety of aerosolized intra-tracheal dornase alfa administration in patients with SARS-CoV-2-induced acute respiratory distress syndrome (ARDS): a structured summary of a study protocol for a randomised controlled trial [O] . J. P. Desilles, C. Gregoire, C. Le Cossec, -1

机译：雾化气管内糖化酶阿尔法治疗SARS-CoV-2诱发的急性呼吸窘迫综合征（ARDS）患者的疗效和安全性：一项随机对照试验研究方案的结构摘要
7. Protocol for TRAUMADORNASE: a prospective, randomized, multicentre, double-blinded, placebo-controlled clinical trial of aerosolized dornase alfa to reduce the incidence of moderate-to-severe hypoxaemia in ventilated trauma patients [O] . Julien Pottecher, Eric Noll, Marie Borel, 2020

机译：创伤酶协议：雾化DORNASE ALFA的前瞻性，随机，多环境，双盲，安慰剂对照临床试验，降低通风创伤患者中度至严重的低氧血症的发病率

Protocol for TRAUMADORNASE: a prospective randomized multicentre double-blinded placebo-controlled clinical trial of aerosolized dornase alfa to reduce the incidence of moderate-to-severe hypoxaemia in ventilated trauma patients

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