首页> 美国卫生研究院文献>Current Controlled Trials in Cardiovascular Medicine >Upfront radical surgery with total mesorectal excision followed by adjuvant FOLFOX chemotherapy for locally advanced rectal cancer (TME-FOLFOX): an open-label multicenter phase II randomized controlled trial

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Upfront radical surgery with total mesorectal excision followed by adjuvant FOLFOX chemotherapy for locally advanced rectal cancer (TME-FOLFOX): an open-label multicenter phase II randomized controlled trial

机译：全直肠系膜全切除的前期根治性手术然后辅以FOLFOX化疗治疗局部晚期直肠癌（TME-FOLFOX）：一项开放性多中心II期随机对照试验

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Flow diagram of the trial. DFS disease-free survival, OS overall survival, TME total mesorectal excision, CRT chemoradiotherapy, mFOLFOX modified FOLFOX, folinic acid (or leucovorin), 5-fluorouracil, and oxaliplatin

机译：试用流程图。 DFS无病生存期，OS总体生存期，TME全直肠系膜切除术，CRT放化疗，mFOLFOX修饰的FOLFOX，亚叶酸（或亚叶酸），5-氟尿嘧啶和奥沙利铂

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期刊名称 Current Controlled Trials in Cardiovascular Medicine
作者
Jii Bum Lee; Han Sang Kim; Inkyung Jung; Sang Joon Shin; Seung Hoon Beom; Jee Suk Chang; Woong Sub Koom; Tae Il Kim; Hyuk Hur; Byung Soh Min; Nam Kyu Kim; Sohee Park; Seung-Yong Jeong; Jeong-Heum Baek; Seon Hahn Kim; Joon Seok Lim; Kang Young Lee; Joong Bae Ahn;
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年(卷),期 2020(21),-1
年度 2020
页码 -1
总页数 7
原文格式 PDF
正文语种
中图分类心血管疾病;
关键词
Adjuvant chemotherapy; Clinical trial; FOLFOX; Locally advanced rectal cancer; Total mesorectal excision;

机译：辅助化疗;临床试验;FOLFOX;局部晚期直肠癌;直肠系膜全切;

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专利

1. Upfront radical surgery with total mesorectal excision followed by adjuvant FOLFOX chemotherapy for locally advanced rectal cancer (TME-FOLFOX): an open-label, multicenter, phase II randomized controlled trial [J] . Jii Bum Lee, Han Sang Kim, Inkyung Jung, Trials . 2020,第1期

机译：全部介性切除的前期自由基手术，然后进行佐剂Folfox化疗，用于局部晚期直肠癌（TME-FOLFOX）：开放标签，多中心，第二期随机对照试验
2. Organ Preservation in Rectal Adenocarcinoma: a phase II randomized controlled trial evaluating 3-year disease-free survival in patients with locally advanced rectal cancer treated with chemoradiation plus induction or consolidation chemotherapy, and total mesorectal excision or nonoperative management [J] . J. Joshua Smith, Oliver S. Chow, Marc J. Gollub, BMC Cancer . 2015,第1期

机译：直肠腺癌的器官保存：一项II期随机对照试验，评估了局部晚期直肠癌患者的3年无病生存率，这些患者接受化学放疗，诱导或巩固化疗以及全直肠系膜切除或非手术治疗
3. PHASE III MULTICENTER, PROSPECTIVE, CONTROLLED, RANDOMIZED TRIAL TO EVALUATE THE SAFETY AND EFFICACY OF TREATMENT OF RECTAL CANCER T2-T3S (SUPERFICIAL) N0, M0 WITH PREOPERATIVE CHEMORADIOTHERAPY AND TRANSANAL ENDOSCOPIC MICROSURGERY VERSUS TOTAL MESORECTAL EXCISION. PRELIMINARY RESULTS [J] . Serra-Aracil X., Mora L., Pericay C., Diseases of the Colon and Rectum . 2015,第5期

机译：III期多中心，可预测，可控制的随机试验，用于评估直肠癌T2-T3S（特效）N0，M0的术前化学放疗和经鼻内镜下直肠癌直肠癌手术对手术的安全性和有效性。初步结果
4. Organ Preservation in Rectal Adenocarcinoma: a phase II randomized controlled trial evaluating 3-year disease-free survival in patients with locally advanced rectal cancer treated with chemoradiation plus induction or consolidation chemotherapy and total mesorectal excision or nonoperative management [O] . J. Joshua Smith, Oliver S. Chow, Marc J. Gollub, 2015

机译：直肠腺癌的器官保存：一项II期随机对照试验评估在局部晚期直肠癌患者中进行化学放疗诱导或巩固化疗以及全直肠系膜切除或非手术治疗的3年无病生存率
5. Upfront radical surgery with total mesorectal excision followed by adjuvant FOLFOX chemotherapy for locally advanced rectal cancer (TME-FOLFOX): an open-label, multicenter, phase II randomized controlled trial [O] . Jii Bum Lee, Han Sang Kim, Inkyung Jung, 2020

机译：全部介性切除的前期自由基手术，然后进行佐剂Folfox化疗，用于局部晚期直肠癌（TME-FOLFOX）：开放标签，多中心，第二期随机对照试验

Upfront radical surgery with total mesorectal excision followed by adjuvant FOLFOX chemotherapy for locally advanced rectal cancer (TME-FOLFOX): an open-label multicenter phase II randomized controlled trial

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