Comparison of 6  hydroxyethyl starch and 5  albumin for volume replacement therapy in patients undergoing cystectomy (CHART): study protocol for a randomized controlled trial

摘要

BackgroundThe use of artificial colloids is currently controversial, especially in Central Europe Several studies demonstrated a worse outcome in intensive care unit patients with the use of hydroxyethyl starch. This recently even led to a drug warning about use of hydroxyethyl starch products in patients admitted to the intensive care unit. The data on hydroxyethyl starch in non–critically ill patients are insufficient to support perioperative use.