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A Single Intramuscular Dose of a Plant-Made Virus-Like Particle Vaccine Elicits a Balanced Humoral and Cellular Response and Protects Young and Aged Mice from Influenza H1N1 Virus Challenge despite a Modest/Absent Humoral Response

机译：肌内注射类似植物病毒颗粒疫苗的单次肌内剂量可实现均衡的体液和细胞反应并在适度/缺乏体液反应的情况下保护年轻和老年小鼠免受H1N1流感病毒的攻击

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期刊名称 Clinical and Diagnostic Laboratory Immunology
作者
Breanna Hodgins; Karen K. Yam; Kaitlin Winter; Stephane Pillet; Nathalie Landry; Brian J. Ward;
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作者单位

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年(卷),期 2017(24),12
年度 2017
页码 e00273-17
总页数 14
原文格式 PDF
正文语种
中图分类免疫学;
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1. A Single Intramuscular Dose of a Plant-Made Virus-Like Particle Vaccine Elicits a Balanced Humoral and Cellular Response and Protects Young and Aged Mice from Influenza H1N1 Virus Challenge despite a Modest/Absent Humoral Response [J] . Breanna Hodgins, Karen K. Yam, Kaitlin Winter, Clinical and vaccine immunology: CVI . 2017,第12期

机译：肌内注射类似植物病毒颗粒疫苗的单次肌内剂量可实现均衡的体液和细胞反应，并且尽管体液反应适度/缺乏，仍可保护年轻和老年小鼠免受H1N1流感病毒的攻击。
2. Virus-like particles presenting flagellin exhibit unique adjuvant effects on eliciting T helper type 1 humoral and cellular immune responses to poor immunogenic influenza virus M2e protein vaccine [J] . Kim Ki-Hye, Kwon Young-Man, Lee Young-Tae, Virology . 2018,第期

机译：呈现鞭毛蛋白的病毒样颗粒对引发T辅助剂1型体液和细胞免疫反应对免疫原性流感病毒M2E蛋白疫苗的血液疫苗有独特的佐剂作用
3. Vaccination with coxsackievirus B3 virus-like particles elicits humoralTI Vaccination with coxsackievirus B3 virus-like particles elicits humoral immune response and protects mice against myocarditis [J] . Zhang L, Parham NJ, Zhang F, Vaccine . 2012,第13期

机译：柯萨奇病毒B3病毒样颗粒疫苗引起体液免疫柯萨奇病毒B3病毒样颗粒疫苗引起体液免疫反应并保护小鼠免于心肌炎
4. Efficacy of swine influenza virus replicon particle vaccination including cellular and humoral responses after challenge [C] . Annual Meeting of the American Association of Swine Veterinarians . 2018

机译：猪流感病毒复制子颗粒疫苗接种的功效，包括攻击后细胞和体液反应
5. Virus-like particles presenting flagellin exhibit unique adjuvant effects on eliciting T helper type 1 humoral and cellular immune responses to poor immunogenic influenza virus M2e protein vaccine [O] . Ki-Hye Kim, Young-Man Kwon, Young-Tae Lee, -1

机译：呈现鞭毛蛋白的病毒样颗粒对引发T型辅助1型体液和细胞免疫应答对免疫原性较差的流感病毒M2e蛋白疫苗表现出独特的佐剂作用
6. Virus-like particles presenting flagellin exhibit unique adjuvant effects on eliciting T helper type 1 humoral and cellular immune responses to poor immunogenic influenza virus M2e protein vaccine [O] . Ki-Hye Kim, Young-Man Kwon, Young-Tae Lee, 2018

机译：呈现鞭毛蛋白的病毒样颗粒对引发T辅助剂1型体液和细胞免疫反应对免疫原性流感病毒M2E蛋白疫苗的血液疫苗有独特的佐剂作用
7. Multi-Agent Alphavirus DNA Vaccine Delivered by Intramuscular Electroporation Elicits Robust and Durable Virus Specific Immune Responses in Mice and Rabbits and Completely Protects Mice against Lethal Venezuelan, Western, and Eastern Equine Encephalitis Virus Aerosol Challenges. [R] . Dupuy, L. C., Richards, M. J., Livingston, B. D., 2016

机译：通过肌内电穿孔提供的多剂甲病毒DNa疫苗在小鼠和家兔中引发健壮和耐久的病毒特异性免疫应答，并完全保护小鼠免受致命的委内瑞拉，西方和东方马脑炎病毒气溶胶挑战。

A Single Intramuscular Dose of a Plant-Made Virus-Like Particle Vaccine Elicits a Balanced Humoral and Cellular Response and Protects Young and Aged Mice from Influenza H1N1 Virus Challenge despite a Modest/Absent Humoral Response

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