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Perforating Granuloma Annulare Appearing as a Psoriasiform Lesion

机译:穿孔肉芽肿环状显示为牛皮癣样病变

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摘要

We present a 54-year-old Caucasian female with a history of diabetes mellitus, multiple sclerosis, and ulcerative colitis who presented with nail dystrophy, polyarthralgia in her hands and hips, myalgia, proximal myopathy, dactylitis, and psoriasiform-appearing progressive, painful plaques on the dorsal aspect of her hands. Histologic examination of the lesion from the left index finger revealed an interstitial and necrobiotic granulomatous dermatitis with connective tissue mucin deposition associated with a perivascular lymphoid infiltrate. Additionally, there was focal transepidermal elimination of the necrobiotic material. She was diagnosed with perforating granuloma annulare (PGA). We are unaware of any other cases of PGA in the literature with this presentation.
机译:我们介绍了一位54岁的白人女性,有糖尿病,多发性硬化症和溃疡性结肠炎的病史,伴有指甲营养不良,手和臀部多关节痛,肌痛,近端肌病,齿根炎和银屑病,表现为进行性,疼痛她的手背侧的斑块。左手食指的组织学检查发现间质性和坏死性肉芽肿性皮炎伴结缔组织粘蛋白沉积,伴有血管周淋巴样浸润。另外,局部坏死材料经皮经皮消除。她被诊断患有穿孔性肉芽肿(PGA)。通过此演示文稿,我们在文献中没有发现其他任何PGA情况。

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