首页> 美国卫生研究院文献>Canadian Journal of Comparative Medicine >A comparison of the efficacy of a live and four inactivated vaccine preparations for the protection of cats against experimental challenge with Chlamydia psittaci.
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A comparison of the efficacy of a live and four inactivated vaccine preparations for the protection of cats against experimental challenge with Chlamydia psittaci.

机译:活疫苗和四种灭活疫苗制剂对猫的抵抗鹦鹉热衣原体实验攻击的保护作用的比较。

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摘要

A commercial live feline-chlamydial vaccine and four experimental inactivated preparations were compared on the basis of clinical protection in cats challenged conjunctivally and intranasally with Chlamydia psittaci. Best protection was afforded by the live vaccine. Good results were also obtained using inactivated preparations of a recent feline conjunctival isolate. Protection did not correlate with the development of complement fixing antibodies but may be related to the induction of a cell mediated response as assessed by the lymphocyte blastogenesis test.
机译:在临床保护的基础上,比较了经鹦鹉热衣原体感染结膜和鼻内攻击的猫的商业活猫衣原体疫苗和四种实验灭活制剂。活疫苗可提供最佳保护。使用最近的猫结膜分离物的灭活制剂也获得了良好的结果。保护作用与补体固定抗体的发展无关,但可能与诱导细胞介导的反应有关,如淋巴细胞生成试验所评估的。

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