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Risk of cancer of the breast after legal abortion during first trimester: a Swedish register study.

机译:瑞典人在妊娠早期合法流产后患乳腺癌的风险:瑞典的一项登记研究。

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摘要

An increase in induced abortions in Sweden has been accompanied by an increase in the incidence of breast cancer of about 40% in women aged 20-44. To assess whether the apparent risk is real the risk of breast cancer was investigated in practically all Swedish women with a history of a legal abortion in the first trimester before the age of 30 during 1966-74 (n = 49,000). The cohort was followed up in the Swedish cancer register to identify cases of breast cancer diagnosed more than five years after the abortion until the end of 1984. The number of observed cases of breast cancer was 65 compared with an expected number of 84.5, estimated from the contemporary Swedish population with due consideration to age, giving a relative risk of 0.8 (95% confidence interval 0.58 to 0.99). Contrary to most earlier reports, this study did not indicate any overall increased risk of breast cancer after an induced abortion in the first trimester in young women.
机译:在瑞典,人工流产的增加伴随着20-44岁女性乳腺癌的发病率增加约40%。为了评估表观风险是否确实存在,在1966-74年间,几乎所有瑞典妇女均在30岁之前的前三个月中有合法流产史,对乳腺癌的风险进行了调查(n = 49,000)。该队列在瑞典癌症登记处进行了随访,以鉴定堕胎后五年以上直至1984年底诊断出的乳腺癌病例。观察到的乳腺癌病例为65例,而根据预期,这一数字为84.5例。当代瑞典人口,适当考虑了年龄,相对风险为0.8(95%置信区间为0.58至0.99)。与大多数较早的报道相反,该研究没有表明年轻妇女在妊娠早期流产后患乳腺癌的总体风险增加。

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