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Value of routine funduscopy in patients with hypertension: systematic review

机译:常规眼底镜检查对高血压患者的价值:系统评价

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摘要

>Objective To evaluate the additional value of funduscopy in the routine management of patients with hypertension.>Design Systematic review.>Participants Adults aged 19 or more with hypertensive retinopathy.>Data sources Medline, Embase, and the Cochrane Library from 1990.>Review methods Studies were included that assessed hypertensive retinopathy with blinding for blood pressure and cardiovascular risk factors. Studies on observer agreement had to be assessed by two or more observers and expressed as a κ statistic. Studies on the association between hypertensive retinopathy and hypertensive organ damage were carried out in patients with hypertension. The association between hypertensive retinopathy and cardiovascular risk was carried out in unselected normotensive and hypertensive people without diabetes mellitus.>Results The assessment of microvascular changes in the retina is limited by large variation between observers. The positive and negative predictive values for the association between hypertensive retinopathy and blood pressure were low (47% to 72% and 32% to 67%, respectively). Associations between retinal microvascular changes and cardiovascular risk were inconsistent, except for retinopathy and stroke. The increased risk of stroke, however, was also present in normotensive people with retinopathy. These studies did not adjust for other indicators of hypertensive organ damage.>Conclusion Evidence is lacking that routine funduscopy is of additional value in the management of hypertensive patients.
机译:>目的以评估眼底镜检查在高血压患者常规治疗中的附加价值。>设计系统评价。>参与者患有高血压的19岁以上成年人>数据来源,Medline,Embase和Cochrane库,始于1990年。>审查方法研究包括评估高血压性视网膜病并不清楚血压和心血管危险因素的研究。关于观察者一致性的研究必须由两个或更多观察者进行评估,并以κ统计量表示。对高血压患者进行了高血压视网膜病变与高血压器官损害之间关系的研究。高血压视网膜病变与心血管风险之间的相关性是在未选择糖尿病的正常血压和高血压人群中进行的。>结果视网膜微血管变化的评估受到观察者之间较大差异的限制。高血压性视网膜病变与血压之间关联的阳性和阴性预测值较低(分别为47%至72%和32%至67%)。视网膜微血管变化与心血管风险之间的关联是不一致的,除了视网膜病变和中风。但是,在血压正常的视网膜病变人群中,中风的风险也增加了。这些研究未对高血压器官损害的其他指标进行调整。>结论。缺乏证据表明常规眼底镜检查对高血压患者的治疗具有附加价值。

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