Haem arginate infusion stimulates haem oxygenase-1 expression in healthy subjects

机译：精氨酸血红素注射液可刺激健康受试者的血红素氧化酶-1表达

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BACKGROUND AND PURPOSEHaem oxygenase 1 (HO-1) is an inducible protein that plays a major protective role in conditions such as ischaemia-reperfusion injury and inflammation. In this study, we have investigated the role of haem arginate (HA) in human male subjects in the modulation of HO-1 expression and its correlation with the GT length polymorphism (GTn) in the promoter of the HO-1 gene.

机译：背景和目的血红素加氧酶1（HO-1）是一种诱导蛋白，在缺血/再灌注损伤和炎症等疾病中起主要保护作用。在这项研究中，我们研究了人类男性受试者中的精氨酸血红素（HA）在HO-1表达调节中的作用及其与HO-1基因启动子中GT长度多态性（GTn）的相关性。

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期刊名称 British Journal of Pharmacology and Chemotherapy
作者
D Doberer; A Haschemi; M Andreas; T-C Zapf; B Clive; M Jeitler; H Heinzl; O Wagner; M Wolzt; M Bilban;
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作者单位

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年(卷),期 2010(161),8
年度 2010
页码 1751–1762
总页数 12
原文格式 PDF
正文语种
中图分类药学;
关键词
haem oxygenase ischaemia-reperfusion injury healthy volunteers polymorphism;

机译：血红素加氧酶;缺血再灌注损伤;健康志愿者;多态性;

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2. Haem oxygenase-1 expression and coronary heart disease--association between levels of haem oxygenase-1 expression and angiographic morphology as well as the quantity of coronary lesions. [J] . Li YG, Wang DM, Chen SM, Acta Cardiologica . 2006,第3期

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4. Effect of 5-aminolevulinic acid on the haem biosynthesis pathway in pancreatic cancer and pancreatic ductal epithelial cell lines [C] . Peter L. Labib, Walid Al-Akkad, Brian R. Davidson, International Photodynamic Association World Congress;Society of Photo-Optical Instrumentation Engineers;International Photodynamic Association . 2019

机译：5-氨基乙酰丙酸对胰腺癌和胰腺导管上皮细胞系血红素生物合成途径的影响
5. Modulation of haem oxygenase-1 by phytochemicals: a novel stratagem in the mitigation of cardiovascular tissue dysfunction [D] . Arqoub, Hadil Abu. 2007

机译：植物化学杂志的调制氧气氧酶-1：一种新型策略在缓解心血管组织功能障碍中
6. Audit of the Use of Regular Haem Arginate Infusions in Patients with Acute Porphyria to Prevent Recurrent Symptoms [O] . Joanne T. Marsden, Simon Guppy, Penelope Stein, 2015

机译：在急性紫癜患者中使用常规血红素精氨酸输注以预防复发症状的审核
7. Haem arginate infusion stimulates haem oxygenase-1 expression in healthy subjects [O] . Doberer, D, Haschemi, A, Andreas, M, 2010

机译：精氨酸血红素注射液可刺激健康受试者的血红素氧化酶-1表达
8. Altered Haem-Haem Interaction and Tissue-Oxygen Supply: A Theoretical Analysis. [R] . Neville, J. R. 1976

机译：改变Haem-Haem相互作用和组织供氧：一个理论分析。

Haem arginate infusion stimulates haem oxygenase-1 expression in healthy subjects

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