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Assessment of tumour viability in human lung cancer xenografts with texture-based image analysis

机译：基于纹理的图像分析评估人肺癌异种移植物中的肿瘤生存力

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摘要

AimsTo build and evaluate an automated method for assessing tumour viability in histological tissue samples using texture features and supervised learning.

机译：目的利用纹理特征和监督学习来建立和评估用于评估组织学组织样品中肿瘤生存能力的自动化方法。

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期刊名称 BMJ Open Access
作者
Riku Turkki; Nina Linder; Tanja Holopainen; Yinhai Wang; Anne Grote; Mikael Lundin; Kari Alitalo; Johan Lundin;
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作者单位

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年(卷),期 -1(68),8
年度 -1
页码 614–621
总页数 8
原文格式 PDF
正文语种
中图分类
关键词
AUTOMATED SCREENING DIGITAL PATHOLOGY tumour necrosis LUNG CANCER IMAGE ANALYSIS;

机译：自动检查;数字病理学;肿瘤坏死;肺癌;图像分析;

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专利

1. Assessment of tumour viability in human lung cancer xenografts withn texture-based image analysis [J] . Turkki Riku, Linder Nina, Holopainen Tanja, Journal of Clinical Pathology . 2015,第8期

机译：基于纹理的图像分析评估人肺癌异种移植物中的肿瘤生存力
2. Clinical relevance of human cancer xenografts as a tool for preclinical assessment: example of in-vivo evaluation of topotecan-based chemotherapy in a panel of human small-cell lung cancer xenografts. [J] . Nemati F, Daniel C, Arvelo Anti-cancer drugs . 2010,第1期

机译：人类癌症异种移植物作为临床前评估工具的临床相关性：一组人类小细胞肺癌异种移植物中基于拓扑替康的化疗的体内评估实例。
3. Acute vascular response to cediranib treatment in human non-small-cell lung cancer xenografts with different tumour stromal architecture [J] . Jiang Yanyan, Allen Danny, Kersemans Veerle, Lung cancer: Journal of the International Association for the Study of Lung Cancer . 2015,第2期

机译：具有不同肿瘤基质结构的人非小细胞肺癌异种移植物中西地尼布治疗的急性血管反应
4. CT image feature analysis in distinguishing radiation fibrosis from tumour recurrence after stereotactic ablative radiotherapy(SABR)for lung cancer: a preliminary study [C] . Sarah A. Mattonen, David A. Palma, Cornells J. A. Haasbeek, Conference on biomedical applications in molecular, structural, and functional imaging . 2013

机译：立体定向消融放疗（SABR）后肺癌的CT图像特征分析与放射复发的区别：初步研究
5. Comparing gene expression profiles of cell culture models with profiles of tumor xenografts and patient tumors: Implications for lung and breast cancers. [D] . Creighton, Chad J. 2006

机译：将细胞培养模型的基因表达谱与异种移植瘤和患者肿瘤谱进行比较：对肺癌和乳腺癌的影响。
6. Acute vascular response to cediranib treatment in human non-small-cell lung cancer xenografts with different tumour stromal architecture [O] . Yanyan Jiang, Danny Allen, Veerle Kersemans, -1

机译：具有不同肿瘤基质结构的人非小细胞肺癌异种移植物中西地尼布治疗的急性血管反应
7. HIT Poster session 1P154Preclinical diastolic dysfunction is related to impaired endothelial function in patients with chronic kidney diseaseP155Early detection of left atrial and left ventricular abnormalities in hypertensive and obese womenP156Right ventricle preserved systolic function irrespective of right ventricular hypertrophy and disease severity in anderson fabry diseaseP157Left atrial volume and function in patients undergoing percutaneous mitral valve repairP158Impact of left ventricular dysfunction on outcomes of patients undergoing direct TAVI with a self-expanding bioprosthesisP159Anatomic Doppler spectrum – retrospective spectral tissue Doppler from ultra high frame rate tissue Doppler imaging for evaluation of tissue deformationP160Phasic dynamics of ischaemic mitral regurgitation after primary coronary intervention in acute myocardial infarction: serial echocardiographic assessment from emergency room to long-term follow-upP161Reproducibility of 3DE RV volumes - novel insights at a regional levelP162Pulmonary vascular capacitance as assessed by echocardiography in pulmonary arterial hypertensionP163Three-dimensional endocardial area strain: a novel parameter for quantitative assessment of global left ventricular systolic functionP164Role of exercise hemodynamics assessed by echocardiography on symptom reduction after MitraClipP165Early identification of ventricular dysfunction in patients with juvenile systemic sclerosisP166Heart failure with and without preserved ejection fraction - the role of biomarkers in the aspect of global longitudinal strainP167Complex systolic deformation of aortic root: insights from two dimensional speckle tracking imageP168Volumetric and deformational imaging usind 2d strain and 3d echocardiography in patients with pulmonary hypertensionP169Influence of pressure load and right ventricular morphology and function on tricuspid regurgitation in pulmonary arterial hypertensionP170Left ventricular myocardial diastolic deformation analysis by 2D speckle tracking echocardiography and relationship with conventional diastolic parameters in chronic aortic regurgitationP171Extracellular volume, and not native T1 time, distinguishes diffuse fibrosis in dilated or hypertrophic cardiomyopathy at 3TP172Left atrial strain is significantly reduced in arterial hypertensionP173Symptomatic severe secondary mitral regurgitation: LV enddiastolic diameter (LVEDD) as preferable parameter for risk stratificationP174Left ventricular mechanics in isolated left bundle branch block at rest and when exercising: exploration of the concept of conductive cardiomyopathyP175Assessment of myocardial scar by 2D contrast echocardiographyP176Chronic pericarditis - expression of a rare disease: Erdheim Chester diseaseP177Aortic arch mechanics with two-dimensional speckle tracking echocardiography to estimate the left ventricular remodelling in hypertensive patientsP178Strain analysis by tissue doppler imaging: comparison of conventional manual measurement with a semi-automated approachP179Distribution of extravascular lung water in heart failure patients assessed by lung ultrasoudP180Surrogate markers for obstructive coronary artery diseaseP181LA deformation and LV longitudinal strain by two-dimensional speckle tracking echocardiography as predictors of postoperative AF development after aortic valve replacement in ASP182Left ventricular diastolic dysfunction in type 2 diabetic patients with non alcoholic fatty liver diseaseP183Myocardial strain by speckle-tracking and evaluation of 3D ejection fraction in drug-induced cardiotoxicity's approach in breast cancer [O] . AB Gevaert, A Borizanova, F Graziani, 2015

机译：HIT墙报1P154Preclinical舒张功能障碍的慢性肾脏diseaseP155Early检测左心房的相关内皮功能受损，左心室异常，高血压和肥胖womenP156Right心室收缩功能正常，不论右心室肥厚和疾病严重程度在安德森法布里diseaseP157Left房容积和经皮二尖瓣修复患者的功能左心室功能障碍与自膨胀生物升降术患者患者患者的结果，来自超高帧速率组织多普勒成像的患者，用于评估缺血二尖瓣复发的组织变形P160平面动力学后在急性心肌梗死冠脉介入干预：从急诊室到三维超声心动图右心室体积的长期跟踪upP161Reproducibility串行超声心动图评价 - 小说由肺动脉高压肺动脉高压术中超声心动图评估的区域SEATP162玻璃血管电容的见解随着少年全身硬化肺源肌腱肌肤，无需保存的射血分数 - 生物标志物在全球纵向菌株的角色在全球纵向菌株P167比分中的一个主动脉根系中的内容：来自二维散斑跟踪Imagep168散热和变形成像的见解，肺高压患者患者患者患者肺动脉高压患者肺动脉高压肺动脉高压术治疗肺动脉高压术治疗的压力载荷和右心室形态和功能通过2D散斑跟踪超声心动图和与常规舒张性参数的关系分析慢性主动脉率高，而不是天然T1的时间，在3TP172LEFT心房菌株中区分扩张或肥厚性心肌病的扩散纤维化在动脉高压症中显着降低了，在动脉高压症P1173例，严重二次二尖瓣重新改善：LV EndDiaal直径（LVEDD）作为休息左侧束分支块中孤立的左束分支块的风险分层P11744444444444444445的概念：探讨了2D对比超声心动图176Chronic心包炎的心肌瘢痕的导电心肌病概念 - 表达罕见具有二维散斑跟踪超声心动图的力学来估算组织多普勒成像的高血压患者左心室重塑：常规人的比较通过半自动方法测量肺血管肺患者肺血管肺水分分布，由肺超声波180surrogalsp181LA变形和LV纵向应变通过二维散斑跟踪超声心动图作为术后AF的预测因子在ASP182LEFT中更换主动脉瓣膜置换后2型糖尿病患者的心室舒张功能障碍非酒精性脂肪肝病患者P183微囊菌株通过斑点跟踪和评估3D乳腺癌中的3D射血分数的评估

Assessment of tumour viability in human lung cancer xenografts with texture-based image analysis

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