首页> 美国卫生研究院文献>BioMed Research International >Early Continence Recovery after Preservation of Maximal Urethral Length until the Level of Verumontanum during Radical Prostatectomy: Primary Oncological and Functional Outcomes after 1 Year of Follow-Up
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Early Continence Recovery after Preservation of Maximal Urethral Length until the Level of Verumontanum during Radical Prostatectomy: Primary Oncological and Functional Outcomes after 1 Year of Follow-Up

机译:保留最大尿道长度后直至根治性前列腺切除术期间维他莫仑水平后的早期尿失禁恢复:随访1年后的主要肿瘤学和功能结局

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摘要

Purpose. To investigate the effect of preventing maximal urethral length until the level of verumontanum during radical prostatectomy on both oncologic and functional outcomes. Patients and Methods. We recruited 329 patients, and they underwent an open radical prostatectomy by a single surgeon. The study cohort was randomized in 2 groups. A standard radical prostatectomy was performed in group A patients, while in group B the urethra was preserved until the level of verumontanum. Results. There was no statistically significant difference between the study groups in terms of positive surgical margins or biochemical relapse. Regarding the functional results, the incidence of incontinence, urgency, and nocturia at 1st month, statistically significant higher rates were seen in group A. In addition, there was a statistically significant difference in the number of pads/day in favor of group B at the 1st, 3rd, and 6th months after surgery. However, this difference was eliminated at 12 months postoperatively. Similar results were seen with the scores of the ICIQ-SF and IIQ-SF questionnaires. Conclusions. Without compromising the oncological outcome, our surgical modificated technique showed earlier recovery of continence in the first 6 months, having though the same rates of continence at 12 months.
机译:目的。目的探讨在根治性前列腺切除术中预防最大尿道长度直到尿液中铜的水平对肿瘤和功能结局的影响。患者和方法。我们招募了329例患者,他们由一名外科医生进行了根治性前列腺癌根治术。该研究队列被随机分为两组。 A组患者进行了标准的根治性前列腺切除术,而B组中的尿道被保留直至达到Verumontanum的水平。结果。研究组之间在手术切缘阳性或生化复发方面无统计学差异。关于功能性结果,尿失禁,尿急和夜尿的发生率,在A组中观察到统计学上较高的发生率。此外,在B组,每天使用的护垫数在统计学上有显着差异。手术后的第一,第三和第六个月。但是,这种差异在术后12个月时被消除。 ICIQ-SF和IIQ-SF问卷的得分也得出了相似的结果。结论。在不影响肿瘤治疗结果的前提下,我们的外科改良技术显示出头6个月的尿失禁较早恢复,尽管12个月的尿失禁率相同。

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