Development Application and Results from a Precision-medicine Platform that Personalizes Multi-modal Treatment Plans for Mild Alzheimer’s Disease and At-risk Individuals

摘要

Introduction: Alzheimer’s Disease (AD) is a progressive neurodegenerative condition in which individuals exhibit memory loss, dementia, and impaired metabolism. Nearly all previous sin-gle-treatment studies to treat AD have failed, likely because it is a complex disease with multiple un-derlying drivers contributing to risk, onset, and progression. Here, we explored the efficacy of a mul-ti-therapy approach based on the disease risk factor status specific to individuals with AD diagnosis or concern.