Enhanced Water Dispersibility of Curcumin Encapsulated in Alginate-polysorbate 80 Nano Particles and Bioavailability in Healthy Human Volunteers

摘要

Background: The turmeric (Curcuma longa) plant, a perennial herb of the ginger family, is an agronomic crop in the south and southeast tropical Asia. Turmeric an Indian yellow gold and universal spice is described in Ayurveda, an ancient treatise on longevity and quality life for the treatment of various inflammatory disorders. The oral bioavailability of curcumin is low due to poor aqueous solubility, alkaline instability and speedy elimination.