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Comparison of Bayesian models to estimatedirect genomic values in multi-breed commercial beef cattle

机译:贝叶斯模型比较以进行估计多品种商品肉牛的直接基因组价值

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摘要

BackgroundWhile several studies have examined the accuracy of direct genomic breeding values (DGV) within and across purebred cattle populations, the accuracy of DGV in crossbred or multi-breed cattle populations has been less well examined. Interest in the use of genomic tools for both selection and management has increased within the hybrid seedstock and commercial cattle sectors and research is needed to determine their efficacy. We predicted DGV for six traits using training populations of various sizes and alternative Bayesian models for a population of 3240 crossbred animals. Our objective was to compare alternate models with different assumptions regarding the distributions of single nucleotide polymorphism (SNP) effects to determine the optimal model for enhancing feasibility of multi-breed DGV prediction for the commercial beef industry.
机译:背景技术尽管有几项研究检查了纯种牛种群内部和之间的直接基因组育种值(DGV)的准确性,但对杂交或多育种牛种群中DGV的准确性却缺乏很好的检验。在杂种种子和商业化的牛场中,人们越来越希望使用基因组工具进行选择和管理,因此需要进行研究以确定其功效。我们使用不同大小的训练种群和3240杂交动物种群的替代贝叶斯模型预测了六个性状的DGV。我们的目标是比较关于单核苷酸多态性(SNP)效应分布的具有不同假设的替代模型,以确定用于增强商业牛肉行业多品种DGV预测可行性的最佳模型。

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