术中放射治疗在膀胱癌治疗中的应用分析

摘要

Objective To evaluate the clinical efficacy of intraoperative radiotherapy for bladder cancer. Methods Sixty two patients with bladder cancer admitted in Zhuji People's Hospital from 2002 to 2010 were randomly assigned to two groups:32 cases underwent tumor resection and intraoperative radiotherapy (study group) and 30 cases received tumor resection alone (control group) . The overal survival rate, relapse- free survival, metastasis- free survival and length of hospital stay were com-pared between two groups. Results The patients were fol owed up for>3y with a fol ow- up rate of 100.00%. The overal sur-vival rate, relapse- free survival, and distant metastasis- free survival rate in study group were significantly longer than those in control group (P<0.05);however, there was no difference in length of hospital stay between two groups (P>0.05). Conclusion The intraoperative radiotherapy can effectively improve the overal survival, relapse- free survival and distant metastasis- free sur-vival for patients with bladder cancer.%目的：探讨术中放射治疗膀胱癌的临床疗效。方法选择2002-2010年收治的62例膀胱癌患者，随机分成两组，其中治疗组32例，对照组30例，治疗组患者手术中给予放射治疗，对照组患者给予单纯手术治疗，比较两组患者总生存率、无复发生存率、无远处转移生存率以及住院时间。结果两组患者随访均超过3年，随访率均为100.00%，两组间总生存率、无复发生存率及无远处转移生存率均有统计学差异（均P＜0.05），住院时间无统计学差异（P＞0.05）。结论术中放射治疗膀胱癌疗效显著，可有效提高无复发生存率、无远处转移生存率及总生存率，且不增加术后住院时间，值得在临床上推广使用。