目的 比较丁咯地尔与川芎嗪治疗急性脑梗死的临床疗效及其对血液流变学的影响.方法 62例急性脑梗死患者随机分为两组,每组31例,一组在常规治疗基础上给予川芎嗪注射液治疗,另一组在常规治疗基础上给予地尔注射液治疗,观察两组患者的临床疗效、血液流变学指标.结果 治疗组的显效率和总有效率均明显高于对照组(P<0.01或P<0.05);两组患者治疗后的血液流变学参数均比治疗前有所改善(P<0.05),且治疗组患者各项血液流变学参数的改善均优于对照组(P<0.05).结论 丁咯地尔治疗急性脑梗死比川芎嗪的疗效更佳,且无严重的毒副反应.%Objective To investigate the IMP and buflomcdil for the treatment of acute cerebral embolism (ACE ) and their effects on the blood rhcology. Methods 62 cases with ACE were randomly divided into control group and treatment group from February 2009 to February 2011 in our hospital, and each group had 31 cases. All of the patients were given conventional treatment of the ACE. The control group was given TMP on the basis of the conventional treatment while the treatment group was received buflomcdil on the basis of the conventional treatment. The clinical efficacy and blood Theology were compared between the two groups. Results The rate of significant efficiency and total efficiency in the treatment group were higher than the control grouprn(P<0.01 or P<0.05 ) ; the blood rheology parameters of the post-treatment were better than the pre-treatment ( P<0.05 ) . and the blood rheology parameters in the treatment group were better than the control group ( P<0.05 ) . Conclusion The buflomedil has better efficacy for the treatment of ACE than TMP; it has no serious side effects, and it is suitable for the application in clinical.
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