Objective To investigate the effect of nitrous oxide inhalation combined with misoprostol in abortion.Methods 125 cases pregnancy 42～60d women underwent analgesia from January to November in 2016 were selected in the study.The patients were randomly divided two groups.group A was 63 patients with nitrous oxide inhalation analgesia combined with misoprostol, while group B of 62 patients with nitrous oxide inhalation analgesia simply.Results The effect of analgesic was 100％ in group A, while 81％ in group B, which was significantly difference between two groups (P＜0.05).The degree of cervical relaxation in group A was better than that in group B (P＜0.01).There was significantly difference between group A and group B for the operation time (P=0.045).There was no significantly difference in blood loss and adverse reaction rate between the two groups (P＞0.05).Conclusion Inhalation analgesia combined with misoprostol in the abortion analgesic effect is satisfactory, and less adverse reactions, it is worthy of promotion.%目的 观察笑气吸入镇痛联合米索前列醇口服在人工流产术中的应用效果.方法 2016年1月至11月孕42～60d,愿意接受镇痛人工流产的妇女125例,随机分为2组,A组63例采用笑气吸入镇痛联合米索前列醇口服,B组62例采用单纯笑气吸入镇痛.结果 A组镇痛有效率100％,B组镇痛有效率81％,两组比较差异有统计学意义(P＜0.05);A组宫颈松弛度优于B组(P＜0.01),A组手术时间与B组比较,差异有统计学意义(P=0.045);两组术中出血量、不良反应率比较差异无统计学意义(P＞0.05).结论 笑气吸入镇痛联合米索前列醇口服给药在人工流产术中镇痛效果好,不良反应少,值得在基层医院推广.
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