Objective: To study the effect of moxibustion on the anti-oxidative capacity of brain tissue in D-galactose-induced aging rats. Methods: Male SD rats were subcutaneously injected with D-galactose to establish the subacute aging rat models. The 40 rats were randomly divided into the D-galactose injection group(n = 10), the D-galactose injection with moxibustion group(n = 10), the D-galactose injection with piracetam group(n = 10) and the untreated group as control(n = 10) following the random number table. The spectrophotometry was applied to detect the changes of SOD activity and MDA level in the rat brains. Results: Diminished SOD activity and elevated MDA level in the rat brains were shown with injection of D-galactose in contrast to the baseline in the untreated group, as moxibustion treatment was able to reverse the changes of SOD activity and MDA level. Conclusion: Moxibustion therapy can attenuate the aging process by increasing anti-oxidative capacity in rat brains.%目的 研究艾灸对D-半乳糖所致衰老大鼠脑组织抗氧化能力的影响.方法 雄性SD 大鼠采用D-半乳糖皮下 注射制备亚急性衰老大鼠模型,随机数字表法分为模型组、艾灸组、吡拉西坦组,每组保证10 只,设置正常组10 只作为对 照.分光光度法检测大鼠脑组织SOD 活性、MDA 水平的变化.结果 与正常组相比,模型组大鼠脑组织SOD 活性降低,MDA 水平升高 .与模型组相比,艾灸组大鼠脑组织SOD 活性升高,MDA 水平下降.结论 艾灸可通过增强衰老大鼠脑组织抗氧化能力,达到 延缓衰老的目的.
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