Research Progress on the Intervening Effects of Active Components of Chinese Herbs on Amyloid-Beta-Induced Injury of Neural Cells

摘要

Alzheimer’s disease is a common clinical central nervous system degenerative disease.From 1906,it has not yet been clearly revealed the pathogenesis,and there are no clinically safe and effective drugs.Amyloid-beta（Aβ）cascade reaction theory is currently recognized as the pathogenesis.Aβdeposition of neurotoxicity is an important part of the pathogenesis.There are Aβ-induced inflammation of the central nervous and oxidative stress-induced apoptosis induced by a variety of ways leading to neuronal dysfunction and death.This article summarizes the active ingredients of traditional Chinese medicine that has a protective effect on Aβtoxicity in recent years.Traditional Chinese medicine mainly through the antiapoptosis,antioxidation,and anti-inflammatory reduces Aβproduction and deposition of Aβon the protection of nerve cell injury.