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The role of advanced glycation end products and their mechanism in DN

         

摘要

Advanced glycation end products(AGEs), which are macromolecular material such as proteins, lipids, and nucleic acids free amino and reducing sugar on the reaction of aldehyde group under the condition of the enzyme, generate the stable compounds. AGEs formation is enhanced in diabetes and is associated with the development of diabetic complications. AGEs, as an important marker of chronic complications of diabetes mellitus, plays an important role in the development and progression of diabetic nephropathy. In the current review, we discuss mechanisms and the role of AGEs in diabetic nephropathy.

著录项

  • 来源
    《世界中西医结合杂志(英文)》 |2017年第003期|P.8-11|共4页
  • 作者单位

    Heilongjiang University of Traditional Chinese Medicine;

    The First Affiliated Hospital of Heilongjiang University of Chinese Medicine;

    The First Affiliated Hospital of Anhui University of Chinese Medicine;

    Heilongjiang University of Traditional Chinese Medicine;

    The First Affiliated Hospital of Heilongjiang University of Chinese Medicine;

    The First Affiliated Hospital of Anhui University of Chinese Medicine;

    Heilongjiang University of Traditional Chinese Medicine;

    The First Affiliated Hospital of Heilongjiang University of Chinese Medicine;

    The First Affiliated Hospital of Anhui University of Chinese Medicine;

    Heilongjiang University of Traditional Chinese Medicine;

    The First Affiliated Hospital of Heilongjiang University of Chinese Medicine;

    The First Affiliated Hospital of Anhui University of Chinese Medicine;

  • 原文格式 PDF
  • 正文语种 CHI
  • 中图分类 糖尿病性昏迷及其他并发症;
  • 关键词

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