Nardostachys jatamansi extract protects against cytokine-induced β-cell damage and streptozotocin-induced diabetes

Mi-Young; Song; Ui-Jin; Bae; Bong-Hee; Lee; Kang-Beom; Kwon; Eun-A; Seo; Sung-Joo; Park; Min-Sun; Kim; Ho-Joon; Song; Keun-Sang; Kwon; Jin-Woo; Park; Do-Gon; Ryu; Byung-Hyun; Park

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Nardostachys jatamansi extract protects against cytokine-induced β-cell damage and streptozotocin-induced diabetes

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AIM: To investigate the anti-diabetogenic mechanism of Nardostachys jatamansi extract (NJE). METHODS: Mice were injected with streptozotocin viaa tail vein to induce diabetes. Rat insulinoma RINm5F cells and isolated rat islets were treated with interleukin1β and interferon-γ to induce cytotoxicity. RESULTS: Treatment of mice with streptozotocin resulted in hyperglycemia and hypoinsulinemia, which was conf irmed by immunohistochemical staining of the islets. The diabetogenic effects of streptozotocin were c...

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《世界胃肠病学杂志：英文版》 |2010年第026期|P.|共1页
作者
Mi-Young; Song; Ui-Jin; Bae; Bong-Hee; Lee; Kang-Beom; Kwon; Eun-A; Seo; Sung-Joo; Park; Min-Sun; Kim; Ho-Joon; Song; Keun-Sang; Kwon; Jin-Woo; Park; Do-Gon; Ryu; Byung-Hyun; Park;
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作者单位

Department;

of;

Biochemistry;

Medical;

School;

and;

Diabetes;

Research;

Center;

Chonbuk;

National;

University;

Jeonju;

Jeonbuk;

561-756;

South;

Korea;

Department;

of;

Physiology;

School;

of;

Oriental;

Medicine;

Wonkwang;

University;

Iksan;

Jeonbuk;

570-749;

Department;

of;

Food;

and;

Nutrition;

School;

of;

Human;

Environmental;

Science;

Department;

of;

Herbology;

Department;

of;

Preventive;

Medicine;

Medical;

School;

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原文格式 PDF
正文语种 CHI
中图分类糖尿病;
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Nardostachys jatamansi extract protects against cytokine-induced β-cell damage and streptozotocin-induced diabetes

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