EFFECTS OF ELECTROACUPUNCTURE ON PLASMA CATECHOLAMINE AND ANGIOTENSION Ⅱ IN OPEN HEART SURGICAL PATIENTS UNDERGOING CARDIOPULMONARY BYPASS

摘要

To study the effects of electroacupuncture on sympathetic adrenomedullary(SA) system and renin angiotensin aldosterone (RAA) system in open heart surgical patients undergoing cardiopulmonary bypass (CPB), 30 patients with atrial septal defect were randomly divided into general anesthesia (GA) group, acupuncture anesthesia (AA) group and acupuncture with general anesthesia (AGA) group. Peripheral blood samples were taken before anesthesia and 30 min after CPB. The plasma concentrations of norepinephrine (NE), epinphrine (E) and angiotensinⅡ(AⅡ) were detected. Results: Plasma NE and E of post CPB increased significantly in GA group and AA group, but decreased significantly in AGA group. Plasma AⅡ of post CPB increased significantly in GA group, but no marked changes were found in AA group and AGA group. Conclusions: Acupuncture can improve the AⅡ response to cardiac surgery and CPB. AGA but not AA can inhibit the catecholamine (CA) response to cardiac surgery and CPB.