丁沉透膈散治疗化疗延迟呕吐临床观察

摘要

Objective:To investigate the therapeutic effect of Dingchen Touge powder for chemotherapy induced gastrointestinal reaction . Methods:A total of 136 patients with delayed chemotherapy-induced vomiting were randomly divided into two groups , in chemotherapy cycle, treatment group was given Dingchen Touge powder orally;while control group was given methoxychlor tome amine and dexametha -sone.Clinical effect and adverse reaction in two groups were observed and compared .Results:The effect for symptoms of anorexia , nau-sea and vomiting in treatment group was obviously superior to control group , and the difference was statistically significant (P<0.05). Conclusion:Dingchen Touge powder has good comprehensive effect on chemotherapy -induced gastrointestinal reaction , and is worthy to be clinically popularized and applied .%目的：观察中药丁沉透膈散治疗肿瘤化疗所致消化道反应的疗效。方法：将136例化疗所致延迟呕吐的患者随机分为2组，在化疗周期中实验组以中药丁沉透膈散汤剂口服；对照组予甲氧氯普胺＋地塞米松，比较2组的临床效果与药物不良反应。结果：实验组在治疗食欲不振、抑制恶心、呕吐等方面明显优于对照组，差异有统计学意义（P值均小于0.05）。结论：中药丁沉透膈散防治化疗药物所致消化道反应综合疗效较好，值得临床推广应用。