舒经化瘀活络法治疗急性软组织损伤疗效观察

摘要

Objective:To observe the curative effect of soothing the channels,transforming stasis and quickening vessels in treating acute soft tissue injury.Methods:An open,randomized,controlled,and prospective study conducted on 430 patients treated in our outpatient department with acute soft tissue injury.Patients were randomly divided into control group and observation group with 215 cases in each. Patients in the control group were given Melilotus Extract Tablet,Diclofenac Diethylamine Emulgel application,and the observation group applied soothing channel method of Dahuoluo pills apart from the same treatment as the control group.Clinical symptoms and blood rheol-ogy index of laboratory after one treatment course.The final curative rate and healing time were compared before and after treatment after 3 treatment courses.Results:After one treatment course,the effective rate of the observation group was 74.42%,which was higher than that of the control group (39.54%),and the difference was statistically significant (P <0.05).The symptoms including pain,swelling, bruising,dysfunction,the symptoms score and plasma viscosity,hematocrit,fibrinogen,erythrocyte sedimentation rate and blood rheology serum levels of the observation group were all significantly lower than those in the control group,and the the differences were statistically significant (P <0.05);After 3 courses of treatment,the final curative rate of observation group was 97.67%,which was better than that of the control group (81.39%).the observation group took an average of (10.79 ±3.17)days which was significantly decreased com-pared with the control group (15.79 ±3.63)days,and there was significant difference (P <0.05).There was no statistical difference between the two groups in terms of safety (P >0.05).Conclusion:Soothing the channels,transforming stasis and quickening vessels in treating acute soft tissue injury can promote the clinical symptoms,improve blood rheology,shorten the course of disease,and the curative effect is distinct with no serious adverse reactions.%目的：观察舒经化瘀活络法治疗急性软组织损伤的疗效。方法：采用开放、随机、对照、前瞻性研究方法对我科门诊部收诊的430例急性软组织损伤患者进行临床观察。将86例患者按数字表法随机分为对照组和治疗组各215例，对照组给予草木犀流浸液片、双氯芬酸二乙胺乳胶剂应用，治疗组在对照组基础上根据舒经化瘀活络法给予大活络胶囊口服，1个疗程后对比2组治疗前后临床症状及血液流变学等实验室指标，3个疗程时对比最终治愈率及治愈时间。结果：1个疗程时，治疗组愈显率74.42％高于对照组的39.54，差异有统计学意义（P ＜0.05），治疗组疼痛、肿胀、瘀斑、功能障碍等症状、体征评分及血浆黏度、红细胞比容、纤维蛋白原、红细胞沉降率等血液流变学指标血清水平均明显低于对照组，差异均有统计学意义（P ＜0.05），3个疗程后，治疗组最终治愈率97.67％优于对照组的81.39％，治疗组平均用时（10.79±3.17）d，较对照组的（15.79±3.63）d 明显缩短，差异均有统计学意义（P ＜0.05），全部治疗期间，2组安全性无统计学差异（P ＞0.05）。结论：舒经化瘀活络法治疗急性软组织损伤可促进临床症状缓解，改善血液流变性，缩短病程，疗效显著，无严重不良反应。