温中健脾法治疗慢性消化性溃疡及慢性非特异性溃疡性结肠炎临床研究

摘要

目的：探讨温中健脾法治疗虚寒型慢性消化性溃疡及慢性非特异性溃疡的临床疗效。方法：将120例符合中医虚寒证的慢性消化性溃疡及慢性非特异性溃疡性结肠炎患者按1∶1随机分为治疗组60例和对照组60例。治疗组采用温中健脾饮治疗，慢性消化性溃疡采用雷尼替丁对照，慢性非特异性溃疡性结肠炎用柳氮磺吡啶肠溶片进行对照。疗程2个月。结果：中医证候总显效率为75.00％，总有效为83.33％，对照组分别为56.67％和75.00％。治疗组慢性非特异性溃疡性结肠炎疾病疗效评价的显效率为40％，总有效率73.33％，对照组分别为44.44％和80.95％，治疗组慢性消化性溃疡疗效总显效率为42.22％，总有效率73.33％，对照组分别为52.38％和80.95％，组间比较差异无统计学意义（P ＞0.05）.结论：采用芪连片治疗慢性消化性溃疡及慢性非特异性溃疡疗效满意。%Objective:To discuss the clinical efficacy of the Wenzhong Jianpi (middle-warming,spleen-tonifying)method in chro-nic peptic ulcers and chronic non-specific ulcerative cases belonging to the pattern of Xuhan (deficiency-cold).Methods:We randomized 120 cases of Xuhan featured chronic peptic ulcers and chronic non-specific ulcerative colitis patients into a 1∶1 treat-ment group (60 cases)and a control group (60 cases).The treatment group used self-designed prescription Wenzhong Jianpi Yin,the control group adopted ranitidine or sulfasalazine (enteric coated tablets)respectively for a treatment course of two months.Results:For alleviating of TCMsyndrome symptoms,the treatment group had a total significant effective rate of 75.00%, and total effective rate of 83.33%;which were 56.67% and 75.00% of the control group.For treating chronic non-specific ulcer-ative colitis,the treatment group had a total significant effective rate of 40.00% and total effective rate of 73.33%;Control group was at 44.44% and 80.95% respectively.For treating Chronic Peptic Ulcers,the treatment group had a total significant effective rate of 42.22% and total effective rate of 73.33%;Control group was at 52.38% and 80.95% respectively.Group comparison had no statistical significance (P >0.05).Conclusion:Wenzhong Jianpi method has satisfactory efficacy in treating chronic pep-tic ulcers and chronic non-specific ulcerative colitis.