中西医结合治疗胸腰椎不稳定骨折48例

摘要

Objective: To observe the clinical effects of pedicle of vertebral arch fixation combines with HuiSheng DiYiDan in treatment of unstable thoracolumber fracture. Methods: 90 patients were randomly divided into the observation group of 48 cases and the control group of 42 cases. Both groups were treated with pedicle of vertebral arch fixation and postoperative anti-inflammatory therapy. The observation group was further given HuiSheng DiYiDan. Then fracture healing, pain score(PS) of VAS, deformity correction angle of kyphosis and average recovery time of fracture were observed in both groups. Results:Compared the seventh day with the fourteenth day after postoperative score of VAS between two groups, there was statistical difference(P<0.05). After treatment, there was statistical difference(P<0.05) within both groups in deformity correction angle of kyphosis. After 12 months' treatment, there was statistical difference between two groups. There was statistical difference(P<0.05) in overall lost angle after treatment. 46 recovery cases and two effective cases in the observation group, the total effective rate was 100.00%, the average recovery time was(13.7±3.4)weeks; 28 recovery cases, 12 effective cases and two ineffective cases in the control group, the total effective rate was 66.7%, the average recovery time was(17.8±3.6)weeks. There were statistical differences(P<0.05) in clinical effects and average recovery time between two groups. Conclusion: Pedicle of vertebral arch fixation combines with HuiSheng DiYiDan in treatment of unstable thoracolumber fracture can reduce postoperative pain, improve the pace of recovery, enhance recovery rate and reduce missing values of deformity correction angle of kyphosis effectively.%目的:观察经椎弓根内固定术联合回生第一丹治疗胸腰椎不稳定性骨折的临床疗效.方法:将90例患者随机分为观察组48例、对照组42例,2组均采用经椎弓根内固定术,术后抗炎对症治疗.观察组加服回生第一丹.观察2组患者骨折愈合情况、VAS疼痛评分及脊柱后凸畸形矫正角度和骨折平均痊愈时间.结果:VAS评分术后第7天和第14天2组比较,差异有统计学意义(P<0.05).脊柱后凸畸形矫正角2组治疗前后组内比较,差异有统计学意义(P<0.05),治疗后12个月2组比较,差异有统计学意义(P<0.05).总丢失角2组治疗后比较,差异有统计学意义(P<0.05).观察组痊愈46例,有效2例,总有效率100.00%,平均痊愈时间(13.7±3.4)周;对照组痊愈28例,有效12例,无效2例,总有效率66.7%,平均痊愈时间(17.8±3.6)周.临床疗效、平均痊愈时间2组比较,差异有统计学意义(P<0.05).结论:经椎弓根内固定术联合回生第一丹治疗不稳定性胸腰椎骨折能够有效减轻患者术后疼痛,提高愈合速度、增加愈合率,同时能够有效减小脊柱后凸畸形矫正角度丢失值.